Abstract Motivation Since December 2019, the newly identified coronavirus SARS-CoV-2
has caused a massive health crisis worldwide and resulted in over 70 000 COVID-19 …

Tumor cells require a higher supply of nutrients for growth and proliferation than normal
cells. It is well established that metabolic reprograming in cancers for increased nutrient …

Drug discovery efforts for new covalent inhibitors have drastically increased in the last few
years. The binding mechanism of covalent compounds entails the formation of a chemical …

Water‐saving attempts for rice cultivation often reduce yields. Maintaining productivity under
drought is possible when rice genotypes are bred with improved metabolism and spikelet …

Covalent ligands modulating protein activities/signals have attracted unprecedented
attention in recent years, but the insufficient understanding of their advantages in the early …

Background Polyamines play important roles in cell growth and proliferation. Polyamine
metabolism genes are dysregulated in various tumors. Some polyamine metabolism genes …

In less than eight months, the COVID-19 (coronavirus disease 2019) caused by the SARS-
CoV-2 (severe acute respiratory syndrome coronavirus 2) virus has resulted in over …

Functional amino acids (FAA) regulate metabolic pathways directly linked to health, survival,
growth and development. Arginine is a FAA with crucial roles in protein deposition and the …

Personized treatment of breast cancer is still a challenge, and more treatment options for
breast cancer are warranted. Combination therapies have been a highly appreciated …

Hedgehog (Hh) signaling is a critical developmental regulator and its aberrant activation,
due to somatic or germline mutations of genes encoding pathway components, causes …