The mammalian HSP90 family of proteins is a cluster of highly conserved molecules that are
involved in myriad cellular processes. Their distribution in various cellular compartments …

Multiple biologically active components of human milk support infant growth, health and
development. Milk provides a wide spectrum of mammary epithelial cell-derived …

The glucose-regulated proteins (GRPs) are stress-inducible chaperones that mostly reside
in the endoplasmic reticulum or the mitochondria. Recent advances show that the GRPs …

Hsp90 is one of the most important chaperones involved in regulating the maturation of
more than 300 client proteins, many of which are closely associated with refractory diseases …

The endoplasmic reticulum (ER) is a cellular organelle where secretory and membrane
proteins, as well as lipids, are synthesized and modified. When cells are subjected to ER …

Necrotizing enterocolitis (NEC) is characterized by intestinal injury and impaired mucin
synthesis. We recently showed that breast milk exosomes from rodents promote intestinal …

The biophysical rules that govern folding of small, single‐domain proteins in dilute solutions
are now quite well understood. The mechanisms underlying co‐translational folding of …

Abstract Type 2 DCs (DC2s) comprise the majority of conventional DCs within most tumors;
however, little is known about their ability to initiate and sustain antitumor immunity, as most …

Inflammatory bowel disease (IBD) is characterized for dysregulated intestinal inflammation.
Conflicting reports have shown that activation of inflammasome could promote or decrease …

Wnt signaling plays crucial roles in development and tissue homeostasis, and its
dysregulation leads to various diseases, notably cancer. Wnt/β-catenin signaling is initiated …