The complement system in schizophrenia: where are we now and what's next?

JJ Woo, JG Pouget, CC Zai, JL Kennedy - Molecular psychiatry, 2020 - nature.com
The complement system is a set of immune proteins involved in first-line defense against
pathogens and removal of waste materials. Recent evidence has implicated the complement …

Cytokines dysregulation in schizophrenia: a systematic review of psychoneuroimmune relationship

D Rodrigues-Amorim, T Rivera-Baltanas, C Spuch… - Schizophrenia …, 2018 - Elsevier
Introduction: Schizophrenia is a multifactorial psychiatric disease with complex interactions
among the brain and the immune system. A psycho-immune relationship underling …

MMP9/RAGE pathway overactivation mediates redox dysregulation and neuroinflammation, leading to inhibitory/excitatory imbalance: a reverse translation study in …

D Dwir, B Giangreco, L Xin, L Tenenbaum… - Molecular …, 2020 - nature.com
Various mechanisms involved in schizophrenia pathophysiology, such as dopamine
dysregulation, glutamate/NMDA receptor dysfunction, neuroinflammation or redox …

Neutrophil/lymphocyte, platelet/lymphocyte and monocyte/lymphocyte ratios in different stages of schizophrenia

S Özdin, Ö Böke - Psychiatry Research, 2019 - Elsevier
The inflammation hypothesis is frequently mentioned in the pathogenesis of schizophrenia.
The objective of this study was to compare inflammation markers during relapse and …

Bridging Autism Spectrum Disorders and Schizophrenia through inflammation and biomarkers-pre-clinical and clinical investigations

J Prata, SG Santos, MI Almeida, R Coelho… - Journal of …, 2017 - Springer
In recent years, evidence supporting a link between inflammation and neuropsychiatric
disorders has been mounting. Autism spectrum disorders (ASD) and schizophrenia share …

A potential biomarker for treatment stratification in psychosis: evaluation of an [18F] FDOPA PET imaging approach

M Veronese, B Santangelo, S Jauhar… - …, 2021 - nature.com
Abstract [18F] FDOPA PET imaging has shown dopaminergic function indexed as K icer
differs between antipsychotic treatment responders and non-responders. However, the …

Theranostic biomarkers for schizophrenia

M Nikolac Perkovic, G Nedic Erjavec… - International journal of …, 2017 - mdpi.com
Schizophrenia is a highly heritable, chronic, severe, disabling neurodevelopmental brain
disorder with a heterogeneous genetic and neurobiological background, which is still poorly …

Is it possible to predict the future in first-episode psychosis?

J Suvisaari, O Mantere, J Keinänen, T Mäntylä… - Frontiers in …, 2018 - frontiersin.org
The outcome of first-episode psychosis (FEP) is highly variable, ranging from early
sustained recovery to antipsychotic treatment resistance from the onset of illness. For …

Cesarean section or natural childbirth? cesarean birth may damage your health

H Chen, D Tan - Frontiers in psychology, 2019 - frontiersin.org
The increasing popularity of Cesarean birth has become a social concern in many countries.
This paper reviews the literature on the effects of Cesarean section on children's …

A roadmap for the development of applied computational psychiatry

MP Paulus, QJM Huys, TV Maia - Biological psychiatry: cognitive …, 2016 - Elsevier
Computational psychiatry (CP) is a burgeoning field that uses mathematical approaches to
investigate psychiatric disorders, derive quantitative predictions, and integrate data across …