[HTML][HTML] In silico vaccine design: A tutorial in immunoinformatics

DD Martinelli - Healthcare Analytics, 2022 - Elsevier
Immunoinformatics, as a discipline, concerns the application of computational systems to
study the immune system. Recently, the principles of reverse vaccinology have united with …

An overview of in silico vaccine design against different pathogens and cancer

K Kardani, A Bolhassani, A Namvar - Expert Review of Vaccines, 2020 - Taylor & Francis
Introduction Due to overcome the hardness of the vaccine design, computational
vaccinology is emerging widely. Prediction of T cell and B cell epitopes, antigen processing …

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools

FF Gonzalez-Galarza, A McCabe… - Nucleic acids …, 2020 - academic.oup.com
Abstract The Allele Frequency Net Database (AFND, www. allelefrequencies. net) provides
the scientific community with a freely available repository for the storage of frequency data …

Contriving multi-epitope subunit of vaccine for COVID-19: immunoinformatics approaches

R Dong, Z Chu, F Yu, Y Zha - Frontiers in immunology, 2020 - frontiersin.org
COVID-19 has recently become the most serious threat to public health, and its prevalence
has been increasing at an alarming rate. The incubation period for the virus is~ 1–14 days …

Polyelectrolyte-based platforms for the delivery of peptides and proteins

L Zhao, M Skwarczynski, I Toth - ACS Biomaterials Science & …, 2019 - ACS Publications
The use of peptides and proteins in the pharmaceutical field has increased dramatically over
recent years. They have been especially relevant to advances in the treatment of cancer …

Immunoinformatics approach to design multi-epitope-based vaccine against machupo virus taking viral nucleocapsid as a potential candidate

M Naveed, SI Makhdoom, U Ali, K Jabeen, T Aziz… - Vaccines, 2022 - mdpi.com
The family members of Arenaviridae include members of the genus Machupo virus, which
have bi-segmented negative sense RNA inside the envelope and can be transferred to …

In-silico design of an immunoinformatics based multi-epitope vaccine against Leishmania donovani

S Saha, S Vashishtha, B Kundu, M Ghosh - BMC bioinformatics, 2022 - Springer
Abstract Background Visceral Leishmaniasis (VL) is a fatal vector-borne parasitic disorder
occurring mainly in tropical and subtropical regions. VL falls under the category of neglected …

Emerging role of circulating microRNA in the diagnosis of human infectious diseases

R Ojha, R Nandani, RK Pandey… - Journal of cellular …, 2019 - Wiley Online Library
The endogenic microRNAs (miRNA) are evolutionary, conserved, and belong to a group of
small noncoding RNAs with a stretch of 19–24 nucleotides. The miRNAs play an …

Multi-epitope vaccines (MEVs), as a novel strategy against infectious diseases

MM Goumari, I Farhani, N Nezafat… - Current …, 2020 - ingentaconnect.com
Infectious diseases have caused historical pandemics in the world. Three strategies,
including sanitation programs, antimicrobial drugs, and vaccines are considered for the …

Designing of potential polyvalent vaccine model for respiratory syncytial virus by system level immunoinformatics approaches

STQ Naqvi, M Yasmeen, M Ismail… - BioMed Research …, 2021 - Wiley Online Library
Background. Respiratory syncytial virus (RSV) infection is a public health epidemic, leading
to around 3 million hospitalization and about 66,000 deaths each year. It is a life‐threatening …