Thousands of unique non-coding RNA (ncRNA) sequences exist within cells. Work from the
past decade has altered our perception of ncRNAs from'junk'transcriptional products to …

Cancer was initially considered to be an exclusively genetic disease, but an interplay of
dysregulated genetic and epigenetic mechanisms is now known to contribute to the cancer …

Lung cancer is the leading cause of cancer-related mortality worldwide, and its
tumorigenesis involves the accumulation of genetic and epigenetic events in the respiratory …

Although cancer was originally considered a disease driven only by genetic mutations, it has
now been proven that it is also an epigenetic disease driven by DNA hypermethylation …

The majority of human mRNAs generate alternative 3′ untranslated regions (UTRs)
through various processes, including RNA modifications such as RNA editing, m 6 A …

Post-transcriptional modifications have been recently expanded with the addition of RNA
editing, which is predominantly mediated by adenosine and cytidine deaminases acting on …

The nucleoside inosine plays an important role in purine biosynthesis, gene translation, and
modulation of the fate of RNAs. The editing of adenosine to inosine is a widespread post …

The family of adenosine deaminases acting on RNA (ADARs) regulates global gene
expression output by catalyzing adenosine-to-inosine (A-to-I) editing of double-stranded …

The activity of RNA is controlled by different types of post-transcriptional modifications, such
as the addition of methyl groups and other chemical and structural changes, that have been …

DNA alterations have been extensively reported in multiple myeloma (MM); however, they
cannot yet fully explain all the biological and molecular abnormalities in MM, which remains …