Transaminases (TAs) are one of the most promising biocatalysts in organic synthesis for the
preparation of chiral amino compounds. The concise reaction, excellent enantioselectivity …

Highlights•Amine transaminases are extremely important for the synthesis of chiral primary
amines.•Progress has been made towards developing transaminases with broader …

Transaminases have attracted considerable interest in their use as biocatalysts for the
synthesis of compounds containing chiral amine units, which are widespread within the …

Tropane alkaloids (TAs), which are anticholinergic agents, are an essential class of natural
compounds, and there is a growing demand for TAs with anesthetic, analgesic, and …

ω-Transaminases (ω-TA) are attractive biocatalysts for the production of chiral amines from
prochiral ketones via asymmetric synthesis. However, the substrate scope of ω-TAs is …

Transaminases, which catalyze the stereoselective transfer of an amino group between an
amino donor and a prochiral ketone substrate, are interesting biocatalytic tools for the …

Abstract ω‐Transaminases (ω‐TAs) show considerable potential for the synthesis of chiral
amines. However, their low catalytic efficiency towards bulky substrates limits their …

Ketoreductases are tools for the synthesis of chiral alcohols in industry. However, the low
activity of natural enzymes often restricts their use in industrial applications. On the basis of …

Amine transaminases (ATA) have now become frequently used biocatalysts in chemo‐
enzymatic syntheses including industrial applications. They catalyze the transfer of an amine …

The combination of enzymatic and chemical reaction steps is one important area of research
in organic synthesis, preferentially as cascade reactions in one‐pot to improve total …