Applications of multi‐omics analysis in human diseases

C Chen, J Wang, D Pan, X Wang, Y Xu, J Yan… - MedComm, 2023 - Wiley Online Library
Multi‐omics usually refers to the crossover application of multiple high‐throughput screening
technologies represented by genomics, transcriptomics, single‐cell transcriptomics …

[HTML][HTML] A review of omics-based PFAS exposure studies reveals common biochemical response pathways

DJ Beale, GM Sinclair, R Shah, AM Paten… - Science of The Total …, 2022 - Elsevier
Abstract Per and Polyfluoroalkyl Substances (PFAS) are a diverse group of man-made
chemicals with a range of industrial applications and which are widespread in the …

Polystyrene microplastics increase Pb bioaccumulation and health damage in the Chinese mitten crab Eriocheir sinensis

Z Yang, L Zhu, J Liu, Y Cheng, K Waiho, A Chen… - Science of the Total …, 2022 - Elsevier
Microplastics may be potential vectors for environmental contaminants such as heavy metals
in the aquatic ecosystem due to their highly hydrophobic surfaces and fugacity property. To …

Acute hypoxia changes the mode of glucose and lipid utilization in the liver of the largemouth bass (Micropterus salmoides)

JL Sun, LL Zhao, H Wu, Q Liu, L Liao, J Luo… - Science of the Total …, 2020 - Elsevier
Dissolved oxygen (DO) undountedly affects fish distribution, metabolism, and evern survival.
Intensive aquaculture and environmental changes will inevitably lead to hypoxic stress for …

Comparative toxicometabolomics of perfluorooctanoic acid (PFOA) and next-generation perfluoroalkyl substances

KY Gebreab, MNH Eeza, T Bai, Z Zuberi, J Matysik… - Environmental …, 2020 - Elsevier
Owing to environmental health concerns, a number of per-and polyfluoroalkyl substances
(PFAS) have been phased-out, and increasingly replaced by various chemical analogs …

[HTML][HTML] Application of omics-and multi-omics-based techniques for natural product target discovery

HW Zhang, C Lv, LJ Zhang, X Guo, YW Shen… - Biomedicine & …, 2021 - Elsevier
Natural products continue to be an unparalleled source of pharmacologically active lead
compounds because of their unprecedented structures and unique biological activities …

[HTML][HTML] Plasma levels of per-and polyfluoroalkyl substances (PFAS) are associated with altered levels of proteins previously linked to inflammation, metabolism and …

L Dunder, S Salihovic, PM Lind, S Elmståhl… - Environment …, 2023 - Elsevier
Background Per-and polyfluoroalkyl substances (PFAS) have been linked to immunotoxic
and cardiometabolic effects in both experimental and epidemiological studies, but with …

Less is more: a new perspective for toxicity of emerging contaminants by structures, protein adducts and proteomics

X Hu, S Gong, Q He, JL Wu, N Li - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Emerging contaminants, as a group of trace contaminants arising from pharmaceuticals,
personal care products, etc., are of growing concern due to their potential hazard to the …

Golden pompano (Trachinotus blochii) adapts to acute hypoxic stress by altering the preferred mode of energy metabolism

JL Sun, YF Liu, T Jiang, YQ Li, FB Song, X Wen, J Luo - Aquaculture, 2021 - Elsevier
The golden pompano (Trachinotus blochii) is becoming increasingly popular among
consumers for its delicate meat and high nutritional value. High farming density …

Environmental estrogens in surface water and their interaction with microalgae: A review

Y Ma, W Shen, T Tang, Z Li, R Dai - Science of the Total Environment, 2022 - Elsevier
Environmental estrogens (EEs) have received extensive attention because they interfere
with biological endocrine and reproduction systems by mimicking, antagonizing, or …