Local antibiotic delivery options in prosthetic joint infection

W Steadman, PR Chapman, M Schuetz, B Schmutz… - Antibiotics, 2023 - mdpi.com
Prosthetic Joint Infection (PJI) causes significant morbidity and mortality for patients globally.
Delivery of antibiotics to the site of infection has potential to improve the treatment outcomes …

Bioceramics: a review on design concepts toward tailor-made (multi)-functional materials for tissue engineering applications

R Kumar, I Pattanayak, PA Dash, S Mohanty - Journal of Materials Science, 2023 - Springer
Since the second half of the 20th century, bioceramics are widely used as a substitute for
hard tissue engineering. Bioceramics including zirconia, alumina, hydroxyapatite, and …

Antibacterial honeycomb scaffolds for achieving infection prevention and bone regeneration

K Hayashi, M Shimabukuro… - ACS Applied Materials & …, 2022 - ACS Publications
Surgical site infection (SSI) is a severe complication associated with orthopedic bone
reconstruction. For both infection prevention and bone regeneration, the framework surface …

Biological aspects to enhance fracture healing

PL Rodham, VP Giannoudis… - EFORT Open …, 2023 - eor.bioscientifica.com
The ability to enhance fracture healing is paramount in modern orthopaedic trauma,
particularly in the management of challenging cases including peri-prosthetic fractures, non …

Debridement, Antibiotic Pearls, and Retention of the Implant (DAPRI) in the Treatment of Early Periprosthetic Joint Infections: A Consecutive Series

PF Indelli, S Ghirardelli, P Valpiana, L Bini, M Festini… - Pathogens, 2023 - mdpi.com
Introduction: Periprosthetic joint infections (PJI) represent a devastating consequence
following total joint arthroplasty (TJA). In this study, the authors describe a modified surgical …

Efficacy and safety of antibiotic impregnated microporous nanohydroxyapatite beads for chronic osteomyelitis treatment: a multicenter, open-label, prospective cohort …

C Jiamton, A Apivatgaroon, S Aunaramwat… - Antibiotics, 2023 - mdpi.com
Chronic osteomyelitis is still a serious health problem that causes disabling conditions and
has an impact on the quality of life. The objective of this study was to determine the clinical …

Calcium phosphate cements as carriers of functional substances for the treatment of bone tissue

Y Lukina, T Safronova, D Smolentsev, O Toshev - Materials, 2023 - mdpi.com
Interest in calcium phosphate cements as materials for the restoration and treatment of bone
tissue defects is still high. Despite commercialization and use in the clinic, the calcium …

Is long time to reimplantation a risk factor for reinfection in two-stage revision for periprosthetic infection? A systematic review of the literature

J Puetzler, M Schulze, G Gosheger, J Schwarze… - Frontiers in …, 2023 - frontiersin.org
The two-stage revision arthroplasty is a common treatment option for chronic periprosthetic
infection (PJI). The time to reimplantation (TTR) reported in the literature varies substantially …

Is the routine use of local antibiotics in the management of periprosthetic joint infections justified?

J Bourget-Murray, M Azad, W Gofton… - Hip …, 2023 - journals.sagepub.com
Periprosthetic joint infection (PJI) following total hip and total knee arthroplasty continues to
be a leading cause of re-operation and revision arthroplasty. Not only is the treatment of PJI …

The use of Stimulan in bone and joint infections: A prospective multicentre study

P Mereddy, SR Nallamilli, VP Gowda… - Bone & Joint …, 2023 - boneandjoint.org.uk
Aims Musculoskeletal infection is a devastating complication in both trauma and elective
orthopaedic surgeries that can result in significant morbidity. Aim of this study was to assess …