The gut-lung axis in health and respiratory diseases: a place for inter-organ and inter-kingdom crosstalks

R Enaud, R Prevel, E Ciarlo, F Beaufils… - Frontiers in cellular …, 2020 - frontiersin.org
The gut and lungs are anatomically distinct, but potential anatomic communications and
complex pathways involving their respective microbiota have reinforced the existence of a …

Gut microbiome, big data and machine learning to promote precision medicine for cancer

G Cammarota, G Ianiro, A Ahern, C Carbone… - Nature reviews …, 2020 - nature.com
The gut microbiome has been implicated in cancer in several ways, as specific microbial
signatures are known to promote cancer development and influence safety, tolerability and …

The microbiome of the upper respiratory tract in health and disease

C Kumpitsch, K Koskinen, V Schöpf… - BMC biology, 2019 - Springer
The human upper respiratory tract (URT) offers a variety of niches for microbial colonization.
Local microbial communities are shaped by the different characteristics of the specific …

Cystic fibrosis and Pseudomonas aeruginosa: the host-microbe interface

S Malhotra, D Hayes Jr, DJ Wozniak - Clinical microbiology …, 2019 - Am Soc Microbiol
In human pathophysiology, the clash between microbial infection and host immunity
contributes to multiple diseases. Cystic fibrosis (CF) is a classical example of this …

Advances in the microbiology of Stenotrophomonas maltophilia

JS Brooke - Clinical microbiology reviews, 2021 - Am Soc Microbiol
Stenotrophomonas maltophilia is an opportunistic pathogen of significant concern to
susceptible patient populations. This pathogen can cause nosocomial and community …

Microbiome epidemiology and association studies in human health

H VanEvery, EA Franzosa, LH Nguyen… - Nature Reviews …, 2023 - nature.com
Studies of the human microbiome share both technical and conceptual similarities with
genome-wide association studies and genetic epidemiology. However, the microbiome has …

Cystic fibrosis lung environment and Pseudomonas aeruginosa infection

AY Bhagirath, Y Li, D Somayajula, M Dadashi… - BMC pulmonary …, 2016 - Springer
Background The airways of patients with cystic fibrosis (CF) are highly complex, subject to
various environmental conditions as well as a distinct microbiota. Pseudomonas aeruginosa …

Progress in therapies for cystic fibrosis

K De Boeck, MD Amaral - The Lancet Respiratory Medicine, 2016 - thelancet.com
Standard follow-up and symptomatic treatment have allowed most patients with cystic
fibrosis to live to young adulthood. However, many patients still die prematurely from …

Gut microbial profile is altered in primary biliary cholangitis and partially restored after UDCA therapy

R Tang, Y Wei, Y Li, W Chen, H Chen, Q Wang, F Yang… - Gut, 2018 - gut.bmj.com
Objective A close relationship between gut microbiota and some chronic liver disorders has
recently been described. Herein, we systematically performed a comparative analysis of the …

Lung function and microbiota diversity in cystic fibrosis

L Cuthbertson, AW Walker, AE Oliver, GB Rogers… - Microbiome, 2020 - Springer
Background Chronic infection and concomitant airway inflammation is the leading cause of
morbidity and mortality for people living with cystic fibrosis (CF). Although chronic infection in …