Progression in migraine: Role of mast cells and pro-inflammatory and anti-inflammatory cytokines

P Conti, C D'Ovidio, C Conti, CE Gallenga… - European journal of …, 2019 - Elsevier
Migraine is a common painful neurovascular disorder usually associated with several
symptoms, such as photophobia, phonophobia, nausea, vomiting and inflammation, and …

Mast cells and sensory nerves contribute to neurogenic inflammation and pruritus in chronic skin inflammation

H Siiskonen, I Harvima - Frontiers in cellular neuroscience, 2019 - frontiersin.org
The intimate interaction between mast cells and sensory nerves can be illustrated by the
wheal and surrounding flare in an urticarial reaction in human skin. This reaction is typically …

Recent advances in our understanding of mast cell activation–or should it be mast cell mediator disorders?

TC Theoharides, I Tsilioni, H Ren - Expert review of clinical …, 2019 - Taylor & Francis
Introduction: An increasing number of patients present with multiple symptoms affecting
many organs including the brain due to multiple mediators released by mast cells. These …

Mast cells in stress, pain, blood-brain barrier, neuroinflammation and Alzheimer's disease

D Kempuraj, S Mentor, R Thangavel… - Frontiers in cellular …, 2019 - frontiersin.org
Mast cell activation plays an important role in stress-mediated disease pathogenesis.
Chronic stress cause or exacerbate aging and age-dependent neurodegenerative diseases …

IL-33 and IL-37: a possible Axis in skin and allergic diseases

F Borgia, P Custurone, F Li Pomi, M Vaccaro… - International journal of …, 2022 - mdpi.com
Interleukin (IL)-37 and IL-33 are among the latest cytokines identified, playing a role in
several inflammatory conditions, spanning from systemic conditions to tumors to localized …

Microglia and mast cells generate proinflammatory cytokines in the brain and worsen inflammatory state: Suppressor effect of IL-37

P Conti, D Lauritano, A Caraffa, CE Gallenga… - European journal of …, 2020 - Elsevier
Brain microglia cells are responsible for recognizing foreign bodies and act by activating
other immune cells. Microglia react against infectious agents that cross the blood-brain …

The potential role of B5: A stitch in time and switch in cytokine

AA Gheita, TA Gheita, SA Kenawy - Phytotherapy Research, 2020 - Wiley Online Library
The wound healing process is a multifaceted sequence of activities associated with tissue
restoration. Novel approaches for the perfection of wound healing have been determined as …

Essential oils and its bioactive compounds modulating cytokines: A systematic review on anti-asthmatic and immunomodulatory properties

GR Gandhi, ABS Vasconcelos, GH Haran… - Phytomedicine, 2020 - Elsevier
Background Asthma, the main inflammatory chronic condition affecting the respiratory
system, is characterized by hyperresponsiveness and reversible airway obstruction …

IL-37 is increased in brains of children with autism spectrum disorder and inhibits human microglia stimulated by neurotensin

I Tsilioni, AB Patel, H Pantazopoulos… - Proceedings of the …, 2019 - National Acad Sciences
Autism spectrum disorder (ASD) does not have a distinct pathogenesis or effective
treatment. Increasing evidence supports the presence of immune dysfunction and …

Anti-inflammatory activity of limonene in the prevention and control of injuries in the respiratory system: A systematic review

HSR Santana, FO de Carvalho, ER Silva… - Current …, 2020 - ingentaconnect.com
Introduction: The pulmonary inflammatory response results from exposure to injurious
factors and is associated with oxidative stress, which intensifies the pathological reaction. In …