Non-coding RNAs in GI cancers: from cancer hallmarks to clinical utility
One of the most unexpected discoveries in molecular oncology, in the last decades, was the
identification of a new layer of protein coding gene regulation by transcripts that do not …
identification of a new layer of protein coding gene regulation by transcripts that do not …
The role of gastric mucosal immunity in gastric diseases
S Nie, Y Yuan - Journal of Immunology Research, 2020 - Wiley Online Library
Gastric mucosa plays its immune function through innate and adaptive immunity by
recruiting immune cells and releasing corresponding cytokines, which have an inseparable …
recruiting immune cells and releasing corresponding cytokines, which have an inseparable …
[HTML][HTML] Advances and key focus areas in gastric cancer immunotherapy: A comprehensive scientometric and clinical trial review (1999-2023)
YN Li, B Xie, Y Zhang, MH He, Y Xing… - World Journal of …, 2023 - ncbi.nlm.nih.gov
BACKGROUND Gastric cancer (GC) is the sixth most common cancer and third leading
cause of cancer-related deaths worldwide. Current treatments mainly rely on surgery-and …
cause of cancer-related deaths worldwide. Current treatments mainly rely on surgery-and …
Phosphodiesterase type 5 inhibitors enhance chemotherapy in preclinical models of esophageal adenocarcinoma by targeting cancer-associated fibroblasts
BP Sharpe, A Hayden, A Manousopoulou, A Cowie… - Cell Reports …, 2022 - cell.com
The chemotherapy resistance of esophageal adenocarcinomas (EACs) is underpinned by
cancer cell extrinsic mechanisms of the tumor microenvironment (TME). We demonstrate …
cancer cell extrinsic mechanisms of the tumor microenvironment (TME). We demonstrate …
Development of an immune-related gene signature for prognosis in melanoma
JA Zhang, XY Zhou, D Huang, C Luan, H Gu… - Frontiers in …, 2021 - frontiersin.org
Melanoma remains a potentially deadly malignant tumor. The incidence of melanoma
continues to rise. Immunotherapy has become a new treatment method and is widely used …
continues to rise. Immunotherapy has become a new treatment method and is widely used …
The expression patterns and prognostic value of the proteasome activator subunit gene family in gastric cancer based on integrated analysis
Y Guo, X Dong, J Jin, Y He - Frontiers in cell and developmental …, 2021 - frontiersin.org
Increasing evidence supports that proteasome activator subunit (PSME) genes play an
indispensable role in multiple tumors. The diverse expression patterns, prognostic value …
indispensable role in multiple tumors. The diverse expression patterns, prognostic value …
Combining the radiomic features and traditional parameters of 18F-FDG PET with clinical profiles to improve prognostic stratification in patients with esophageal …
YH Chen, KH Lue, SC Chu, BS Chang… - Annals of Nuclear …, 2019 - Springer
Objectives To investigate the role of the traditional and radiomic parameters of 18 F-FDG
PET for predicting the outcomes of patients with esophageal squamous cell carcinoma …
PET for predicting the outcomes of patients with esophageal squamous cell carcinoma …
Identification of the relationship between single-cell N6-methyladenosine regulators and the infiltrating immune cells in esophageal carcinoma
Y Bian, G Bi, G Shan, J Liang, G Yao, Q Sui, Z Hu… - Heliyon, 2023 - cell.com
Abstract Background N6-methyladenosine (m 6 A) RNA methylation plays a crucial role in
important genomic processes in a variety of malignancies. However, the characterization of …
important genomic processes in a variety of malignancies. However, the characterization of …
[HTML][HTML] A risk model based on autophagy-related lncRNAs for predicting prognosis and efficacy of immunotherapy and chemotherapy in gastric cancer patients
L Gao, J Xue, X Liu, L Cao, R Wang, L Lei - Aging (Albany NY), 2021 - ncbi.nlm.nih.gov
Long non-coding RNAs (lncRNAs) are a class of non-protein-coding RNAs essential to the
occurrence and development of gastric cancer (GC). We aimed to identify critical lncRNA …
occurrence and development of gastric cancer (GC). We aimed to identify critical lncRNA …
[HTML][HTML] Genomic and epigenomic evolution of acquired resistance to combination therapy in esophageal squamous cell carcinoma
Q Min, Y Wang, Q Wu, X Li, H Teng, J Fan, Y Cao… - JCI insight, 2021 - ncbi.nlm.nih.gov
BACKGROUND Targeted arterial infusion of verapamil combined with chemotherapy
(TVCC) is an effective clinical interventional therapy for esophageal squamous cell …
(TVCC) is an effective clinical interventional therapy for esophageal squamous cell …