Human housekeeping genes are compact

E Eisenberg, EY Levanon - TRENDS in Genetics, 2003 - cell.com
We identify a set of 575 human genes that are expressed in all conditions tested in a publicly
available database of microarray results. Based on this common occurrence, the set is …

Evolution of synonymous codon usage in metazoans

L Duret - Current opinion in genetics & development, 2002 - Elsevier
The vast amount of data generated by genome projects and the recent development of
population genetics models make comparative sequence analyses a very powerful …

Expression pattern and, surprisingly, gene length shape codon usage in Caenorhabditis, Drosophila, and Arabidopsis

L Duret, D Mouchiroud - Proceedings of the National …, 1999 - National Acad Sciences
We measured the expression pattern and analyzed codon usage in 8,133, 1,550, and 2,917
genes, respectively, from Caenorhabditis elegans, Drosophila melanogaster, and …

The extent of codon usage bias in human RNA viruses and its evolutionary origin

GM Jenkins, EC Holmes - Virus research, 2003 - Elsevier
Revealing the determinants of codon usage bias is central to the understanding of factors
governing viral evolution. Herein, we report the results of a survey of codon usage bias in a …

[HTML][HTML] A role for tRNA modifications in genome structure and codon usage

EM Novoa, M Pavon-Eternod, T Pan, LR de Pouplana - Cell, 2012 - cell.com
Transfer RNA (tRNA) gene content is a differentiating feature of genomes that contributes to
the efficiency of the translational apparatus, but the principles shaping tRNA gene copy …

Codon usage bias: causative factors, quantification methods and genome‐wide patterns: with emphasis on insect genomes

SK Behura, DW Severson - Biological Reviews, 2013 - Wiley Online Library
Codon usage bias refers to the phenomenon where specific codons are used more often
than other synonymous codons during translation of genes, the extent of which varies within …

Synonymous Codon Usage in Escherichia coli: Selection for Translational Accuracy

N Stoletzki, A Eyre-Walker - Molecular biology and evolution, 2007 - academic.oup.com
In many organisms, selection acts on synonymous codons to improve translation. However,
the precise basis of this selection remains unclear in the majority of species. Selection could …

Strong Purifying Selection at Synonymous Sites in D. melanogaster

DS Lawrie, PW Messer, R Hershberg, DA Petrov - PLoS genetics, 2013 - journals.plos.org
Synonymous sites are generally assumed to be subject to weak selective constraint. For this
reason, they are often neglected as a possible source of important functional variation. We …

Genomic and evolutionary comparison between SARS-CoV-2 and other human coronaviruses

Z Chen, SS Boon, MH Wang, RWY Chan… - Journal of virological …, 2021 - Elsevier
Three highly pathogenic human coronaviruses can cause severe acute respiratory
syndrome (SARS-CoV, SARS-CoV-2 and MERS-CoV). Although phylogenetic analyses …

Accounting for background nucleotide composition when measuring codon usage bias

JA Novembre - Molecular biology and evolution, 2002 - academic.oup.com
The phenomenon of codon usage bias has been important in the study of evolution because
it provides examples of weak selection working at the molecular level. During the last two …