Obesity and the risk of cardiometabolic diseases

PL Valenzuela, P Carrera-Bastos… - Nature reviews …, 2023 - nature.com
The prevalence of obesity has reached pandemic proportions, and now approximately 25%
of adults in Westernized countries have obesity. Recognized as a major health concern …

[HTML][HTML] Chronic inflammation in the etiology of disease across the life span

D Furman, J Campisi, E Verdin, P Carrera-Bastos… - Nature medicine, 2019 - nature.com
Although intermittent increases in inflammation are critical for survival during physical injury
and infection, recent research has revealed that certain social, environmental and lifestyle …

Molecular aspects of fructose metabolism and metabolic disease

MA Herman, MJ Birnbaum - Cell metabolism, 2021 - cell.com
Excessive sugar consumption is increasingly considered as a contributor to the emerging
epidemics of obesity and the associated cardiometabolic disease. Sugar is added to the diet …

Lifestyle interventions for the prevention and treatment of hypertension

PL Valenzuela, P Carrera-Bastos, BG Gálvez… - Nature Reviews …, 2021 - nature.com
Hypertension affects approximately one third of the world's adult population and is a major
cause of premature death despite considerable advances in pharmacological treatments …

Exercise benefits in cardiovascular disease: beyond attenuation of traditional risk factors

C Fiuza-Luces, A Santos-Lozano, M Joyner… - Nature Reviews …, 2018 - nature.com
Despite strong scientific evidence supporting the benefits of regular exercise for the
prevention and management of cardiovascular disease (CVD), physical inactivity is highly …

Rethinking IL-6 and CRP: Why they are more than inflammatory biomarkers, and why it matters

M Del Giudice, SW Gangestad - Brain, behavior, and immunity, 2018 - Elsevier
Behavioral researchers have increasingly become interested in the idea that chronic, low-
grade inflammation is a pathway through which social and behavioral variables exert long …

The ancestral and industrialized gut microbiota and implications for human health

ED Sonnenburg, JL Sonnenburg - Nature Reviews Microbiology, 2019 - nature.com
Human-associated microbial communities have adapted to environmental pressures. Doses
of antibiotics select for a community with increased antibiotic resistance, inflammation is …

Precision nutrition and the microbiome, part I: current state of the science

S Mills, C Stanton, JA Lane, GJ Smith, RP Ross - Nutrients, 2019 - mdpi.com
The gut microbiota is a highly complex community which evolves and adapts to its host over
a lifetime. It has been described as a virtual organ owing to the myriad of functions it …

Modern-day environmental factors in the pathogenesis of osteoarthritis

F Berenbaum, IJ Wallace, DE Lieberman… - Nature Reviews …, 2018 - nature.com
The prevalence of osteoarthritis (OA) is rising for reasons that are not fully understood. In this
Opinion article, we review the possibility that OA is an evolutionary mismatch disease, which …

Hunter‐gatherers as models in public health

H Pontzer, BM Wood, DA Raichlen - Obesity Reviews, 2018 - Wiley Online Library
Hunter‐gatherer populations are remarkable for their excellent metabolic and
cardiovascular health and thus are often used as models in public health, in an effort to …