Neural mechanisms that make perceptual decisions flexible
Neural mechanisms of perceptual decision making have been extensively studied in
experimental settings that mimic stable environments with repeating stimuli, fixed rules, and …
experimental settings that mimic stable environments with repeating stimuli, fixed rules, and …
Timescales of learning in prefrontal cortex
JA Miller, C Constantinidis - Nature Reviews Neuroscience, 2024 - nature.com
The lateral prefrontal cortex (PFC) in humans and other primates is critical for immediate,
goal-directed behaviour and working memory, which are classically considered distinct from …
goal-directed behaviour and working memory, which are classically considered distinct from …
[HTML][HTML] A dopamine gradient controls access to distributed working memory in the large-scale monkey cortex
Dopamine is required for working memory, but how it modulates the large-scale cortex is
unknown. Here, we report that dopamine receptor density per neuron, measured by …
unknown. Here, we report that dopamine receptor density per neuron, measured by …
Intrinsic timescales as an organizational principle of neural processing across the whole rhesus macaque brain
Hierarchical temporal dynamics are a fundamental computational property of the brain;
however, there are no whole brain, noninvasive investigations into timescales of neural …
however, there are no whole brain, noninvasive investigations into timescales of neural …
[HTML][HTML] Local and long-distance organization of prefrontal cortex circuits in the marmoset brain
The prefrontal cortex (PFC) has dramatically expanded in primates, but its organization and
interactions with other brain regions are only partially understood. We performed high …
interactions with other brain regions are only partially understood. We performed high …
Prefrontal computation as active inference
The prefrontal cortex is vital for a range of cognitive processes, including working memory,
attention, and decision-making. Notably, its absence impairs the performance of tasks …
attention, and decision-making. Notably, its absence impairs the performance of tasks …
Computer code comprehension shares neural resources with formal logical inference in the fronto-parietal network
Despite the importance of programming to modern society, the cognitive and neural bases of
code comprehension are largely unknown. Programming languages might …
code comprehension are largely unknown. Programming languages might …
Prefrontal cortical plasticity during learning of cognitive tasks
Training in working memory tasks is associated with lasting changes in prefrontal cortical
activity. To assess the neural activity changes induced by training, we recorded single units …
activity. To assess the neural activity changes induced by training, we recorded single units …
Decoding working memory information from neurons with and without persistent activity in the primate prefrontal cortex
L Thrower, W Dang, RG Jaffe, JD Sun… - Journal of …, 2023 - journals.physiology.org
Persistent activity of neurons in the prefrontal cortex has been thought to represent the
information maintained in working memory, though alternative models have challenged this …
information maintained in working memory, though alternative models have challenged this …
Long-term learning transforms prefrontal cortex representations during working memory
The role of the lateral prefrontal cortex (lPFC) in working memory (WM) is debated. Non-
human primate (NHP) electrophysiology shows that the lPFC stores WM representations, but …
human primate (NHP) electrophysiology shows that the lPFC stores WM representations, but …