Blood rheology: key parameters, impact on blood flow, role in sickle cell disease and effects of exercise

E Nader, S Skinner, M Romana, R Fort… - Frontiers in …, 2019 - frontiersin.org
Blood viscosity is an important determinant of local flow characteristics, which exhibits shear
thinning behavior: it decreases exponentially with increasing shear rates. Both hematocrit …

Sickle cell disease

GJ Kato, FB Piel, CD Reid, MH Gaston… - Nature reviews Disease …, 2018 - nature.com
Sickle cell disease (SCD) is a group of inherited disorders caused by mutations in HBB,
which encodes haemoglobin subunit β. The incidence is estimated to be between 300,000 …

Recent advances in blood rheology: a review

AN Beris, JS Horner, S Jariwala, MJ Armstrong… - Soft Matter, 2021 - pubs.rsc.org
Due to the potential impact on the diagnosis and treatment of various cardiovascular
diseases, work on the rheology of blood has significantly expanded in the last decade, both …

The vaso‐occlusive pain crisis in sickle cell disease: definition, pathophysiology, and management

DS Darbari, VA Sheehan… - European journal of …, 2020 - Wiley Online Library
Early diagnosis, treatment, and prevention of a vaso‐occlusive crisis (VOC) are critical to the
management of patients with sickle cell disease. It is essential to differentiate between VOC …

The red blood cell—inflammation vicious circle in sickle cell disease

E Nader, M Romana, P Connes - Frontiers in immunology, 2020 - frontiersin.org
Sickle cell disease (SCD) is a genetic disease caused by a single mutation in the β-globin
gene, leading to the production of an abnormal hemoglobin called hemoglobin S (HbS) …

Surface reconstruction engineering with synergistic effect of mixed‐salt passivation treatment toward efficient and stable perovskite solar cells

J Suo, B Yang, E Mosconi, HS Choi… - Advanced Functional …, 2021 - Wiley Online Library
Surface passivation treatment is a widely used strategy to resolve trap‐mediated
nonradiative recombination toward high‐efficiency metal‐halide perovskite photovoltaics …

Physical properties of blood and their relationship to clinical conditions

T Alexy, J Detterich, P Connes, K Toth, E Nader… - Frontiers in …, 2022 - frontiersin.org
It has been long known that blood health heavily influences optimal physiological function.
Abnormalities affecting the physical properties of blood have been implicated in the …

Acute hyperviscosity: syndromes and management

MA Gertz - Blood, The Journal of the American Society of …, 2018 - ashpublications.org
Plasma hyperviscosity is a rare complication of both monoclonal and polyclonal disorders
associated with elevation of immunoglobulins. Asymptomatic patients with an elevation in …

Metabolic influences modulating erythrocyte deformability and eryptosis

JF Brun, E Varlet-Marie, J Myzia… - Metabolites, 2021 - mdpi.com
Many factors in the surrounding environment have been reported to influence erythrocyte
deformability. It is likely that some influences represent reversible changes in erythrocyte …

Nanoparticle properties modulate their attachment and effect on carrier red blood cells

DC Pan, JW Myerson, JS Brenner, PN Patel… - Scientific Reports, 2018 - nature.com
Attachment of nanoparticles (NPs) to the surface of carrier red blood cells (RBCs) profoundly
alters their interactions with the host organism, decelerating NP clearance from the …