In recent decades, the increasing interest in the field of immunotherapy has fostered an
intense investigation of the breast cancer (BC) immune microenvironment. In this context …

This review focuses on immune checkpoint inhibitors–immunomodulatory agents that aim to
relieve tumour-mediated immune-cell suppression. Immune checkpoint proteins can be …

The epidermal growth factor receptor (EGFR) family contains four transmembrane tyrosine
kinases (EGFR1/ErbB1, Her2/ErbB2, Her3/ErbB3 and Her4/ErbB4) and 13 secreted …

The advent of immune-checkpoint inhibitors (ICI) in modern oncology has significantly
improved survival in several cancer settings. A subgroup of women with breast cancer (BC) …

Synergistic therapy strategy and prognostic monitoring of glioblastoma's immune response
to treatment are crucial to optimize patient care and advance clinical outcomes. However …

Simple Summary Tumor-infiltrating lymphocytes (TILs) are immune cells that can be
involved in the anti-tumor response and are presently viewed as a promising, inexpensive …

Breast cancer was traditionally not considered a particularly immunogenic tumor. However,
recent developments have shown that some aggressive triple-negative breast cancers are …

Growing evidence suggests a clear role of the host immune system in HER2+ breast cancer.
In addition, HER2+ breast cancer is generally considered more immunogenic than hormone …

Simple Summary Despite the increased use of neoadjuvant chemotherapy in the early
setting of breast cancer, there is a clinical need for predictive markers of response in daily …

Purpose: We investigated the value of tumor-infiltrating NK (TI-NK) cells and HLA class I
tumor expression as biomarkers of response to neoadjuvant anti-HER2 antibody–based …