Mammosomatotropes: presence and functions in normal and neoplastic pituitary tissue

LS Frawley, FR Boockfor - Endocrine reviews, 1991 - academic.oup.com
I. Introduction M ORE than a half century has passed since Romeis first proposed the “one
cell-one hormone” theory which holds that each of the major pituitary hormones is produced …

Control of growth hormone synthesis

CK Tuggle, A Trenkle - Domestic Animal Endocrinology, 1996 - Elsevier
Growth hormone (GH) is expressed specifically from the somatotroph cells of the anterior
pituitary, and GH transcription is under both cell type-specific and hormonal control (Figure …

Electroporation of bovine spermatozoa to carry foreign DNA in oocytes

MB Gagne, F Pothier, MA Sirard - Molecular reproduction and …, 1991 - Wiley Online Library
In the present study, electroporation was used to test the ability of spermatozoa to carry
foreign DNA into the bovine oocytes. Frozen‐thawed bovine spermatozoa (107/ml) were …

Three transcriptionally distinct forms of Epstein-Barr virus latency in somatic cell hybrids: cell phenotype dependence of virus promoter usage

BM Kerr, AL Lear, M Rowe, D Croom-Carter, LS Young… - Virology, 1992 - Elsevier
Phenotypically distinct human B cell lines display two transcriptionally distinct forms of
Epstein-Barr virus (EBV) latency. Latency I (Lat I) in group I Burkitt's lymphoma (BL) cell lines …

Transcriptional repression in eukaryotes

R Renkawitz - Trends in genetics, 1990 - Elsevier
Gene transcription can be controlled by positive or negative regulatory mechanisms; a
combination of both is frequently responsible for the observed expression patterns. Analysis …

The tissue-specific extinguisher locus TSE1 encodes a regulatory subunit of cAMP-dependent protein kinase

M Boshart, F Weih, M Nichols, G Schütz - Cell, 1991 - cell.com
The tissue-specific extinguisher locus TSEl, a dominant negative regulator of transcription in
somatic cell hybrids, acts via a CAMP response element (CRE) to repress activity of a …

Hepatocyte dedifferentiation and extinction is accompanied by a block in the synthesis of mRNA coding for the transcription factor HNF1/LFB1.

S Cereghini, M Yaniv, R Cortese - The EMBO Journal, 1990 - embopress.org
The promoter proximal sequences of a group of liver‐specific genes including that of
albumin interact with the same hepato‐specific factor named HNF1, LFB1, APF or HP1, a …

αβ lineage-specific expression of the α T cell receptor gene by nearby silencers

A Winoto, D Baltimore - Cell, 1989 - cell.com
T cells expressing either the al3 or yS antigen receptor (TCR) are distinct cell lineages. The
single locus encoding the TCR a and 6 genes requires special regulation to avoid a gene …

Dominant negative regulation of the mouse α-fetoprotein gene in adult liver

J Vacher, SM Tilghman - Science, 1990 - science.org
Transcription of the mouse α-fetoprotein gene is activated in the developing fetal liver and
gut and repressed in both tissues shortly after birth. With germline transformation in mice, a …

A cyclic AMP response element mediates repression of tyrosine aminotransferase gene transcription by the tissue-specific extinguisher locus Tse-1

M Boshart, F Weih, A Schmidt, REK Fournier, G Schütz - Cell, 1990 - cell.com
Tyrosine aminotransferase(TAT) gene expression is liver specific and inducible by
glucocorticoids and via the cAMP signaling pathway. In fibroblasts and other nonliver cells …