[HTML][HTML] Therapeutic strategies against bacterial biofilms

Y Bi, G Xia, C Shi, J Wan, L Liu, Y Chen, Y Wu… - Fundamental …, 2021 - Elsevier
The emergence of multi-drug resistance makes bacterial infection a major threat to public
health and economy. The formation of bacterial biofilms is one of the main reasons of …

Host defense peptide mimicking antimicrobial amino acid polymers and beyond: Design, synthesis and biomedical applications

Y Wu, K Chen, J Wang, M Chen, Y Chen, Y She… - Progress in Polymer …, 2023 - Elsevier
Microbial infections endanger human health and life. Conventional antibiotics has saved
countless human lives, however, is seriously challenged by the quick emergence of …

[HTML][HTML] Advances in the antimicrobial treatment of osteomyelitis

C Zhong, Y Wu, H Lin, R Liu - Composites Part B: Engineering, 2023 - Elsevier
Osteomyelitis is a major complication of orthopedic diseases with high recurrence and
morbidity, along with long hospital stays and high medical costs. The conventional treatment …

Bioinspired intrinsic versatile hydrogel fabricated by amyloidal toxin simulant‐based nanofibrous assemblies for accelerated diabetic wound healing

Q Xuan, F Jiang, H Dong, W Zhang… - Advanced Functional …, 2021 - Wiley Online Library
Persistent microbial infection and decreased neovascularization are common issues
associated with diabetic wound treatment. Hydrogel dressings that offer intrinsic …

Short guanidinium‐functionalized poly (2‐oxazoline) s displaying potent therapeutic efficacy on drug‐resistant fungal infections

W Jiang, M Zhou, Z Cong, J Xie, W Zhang… - Angewandte …, 2022 - Wiley Online Library
New antifungals are urgently needed to combat invasive fungal infections, due to limited
types of available antifungal drugs and frequently encountered side effects, as well as the …

The future of poly (2-oxazoline) s

R Hoogenboom - European Polymer Journal, 2022 - Elsevier
Abstract Poly (2-oxazoline) s have gained significant interest in the past decade, especially
driven by their high potential for biomedical applications, amongst others to substitute poly …

Switching from membrane disrupting to membrane crossing, an effective strategy in designing antibacterial polypeptide

H Zhang, Q Chen, J Xie, Z Cong, C Cao, W Zhang… - Science …, 2023 - science.org
Drug-resistant bacterial infections have caused serious threats to human health and call for
effective antibacterial agents that have low propensity to induce antimicrobial resistance …

Poly (2‐oxazoline) s: a comprehensive overview of polymer structures and their physical properties—an update

S Jana, R Hoogenboom - Polymer International, 2022 - Wiley Online Library
Abstract Poly (2‐alkyl/aryl‐2‐oxazoline) s (PAOxs) have gained immense attraction in the
polymer research community because of their relative ease of microwave‐assisted …

Alternatives to conventional antibiotic therapy: potential therapeutic strategies of combating antimicrobial-resistance and biofilm-related infections

Q Xu, X Hu, Y Wang - Molecular biotechnology, 2021 - Springer
Antibiotics have been denoted as the orthodox therapeutic agents for fighting bacteria-
related infections in clinical practices for decades. Nevertheless, overuse of antibiotics has …

Peptide-mimicking poly (2-oxazoline) displaying potent antibacterial and antibiofilm activities against multidrug-resistant Gram-positive pathogenic bacteria

Z Cong, Z Yan, X Xiao, L Liu, Z Luo, J Zou… - Journal of Materials …, 2025 - Elsevier
The rising prevalence of drug-resistant Gram-positive pathogens, particularly methicillin-
resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci (VRE) …