Emerging importance of satellite glia in nervous system function and dysfunction

M Hanani, DC Spray - Nature Reviews Neuroscience, 2020 - nature.com
Satellite glial cells (SGCs) closely envelop cell bodies of neurons in sensory, sympathetic
and parasympathetic ganglia. This unique organization is not found elsewhere in the …

Psychedelics in psychiatry: neuroplastic, immunomodulatory, and neurotransmitter mechanisms

A Inserra, D De Gregorio, G Gobbi, M Nader - Pharmacological Reviews, 2021 - Elsevier
Mounting evidence suggests safety and efficacy of psychedelic compounds as potential
novel therapeutics in psychiatry. Ketamine has been approved by the Food and Drug …

Neuropathic pain: mechanisms and their clinical implications

SP Cohen, J Mao - Bmj, 2014 - bmj.com
Neuropathic pain can develop after nerve injury, when deleterious changes occur in injured
neurons and along nociceptive and descending modulatory pathways in the central nervous …

Pain modulates dopamine neurons via a spinal–parabrachial–mesencephalic circuit

H Yang, JW de Jong, I Cerniauskas, JR Peck… - Nature …, 2021 - nature.com
Pain decreases the activity of many ventral tegmental area (VTA) dopamine (DA) neurons,
yet the underlying neural circuitry connecting nociception and the DA system is not …

Epigenetic mechanisms of chronic pain

G Descalzi, D Ikegami, T Ushijima, EJ Nestler… - Trends in …, 2015 - cell.com
Neuropathic and inflammatory pain promote a large number of persisting adaptations at the
cellular and molecular level, allowing even transient tissue or nerve damage to elicit …

How to study anxiety and depression in rodent models of chronic pain?

M Kremer, LJ Becker, M Barrot… - European Journal of …, 2021 - Wiley Online Library
Mood disorders such as depression and anxiety are frequently observed in patients
suffering from chronic pain. Over time, different tests and models have been developed in …

Calcium-permeable ion channels in pain signaling

E Bourinet, C Altier, ME Hildebrand… - Physiological …, 2014 - journals.physiology.org
The detection and processing of painful stimuli in afferent sensory neurons is critically
dependent on a wide range of different types of voltage-and ligand-gated ion channels …

Why fish do not feel pain

B Key - Animal Sentience, 2016 - wellbeingintlstudiesrepository.org
Only humans can report feeling pain. In contrast, pain in animals is typically inferred on the
basis of nonverbal behaviour. Unfortunately, these behavioural data can be problematic …

The amygdala between sensation and affect: a role in pain

P Veinante, I Yalcin, M Barrot - Journal of molecular psychiatry, 2013 - Springer
The amygdala is a structure of the temporal lobe thought to be involved in assigning
emotional significance to environmental information and triggering adapted physiological …

Exosomal OTULIN from M2 macrophages promotes the recovery of spinal cord injuries via stimulating Wnt/β-catenin pathway-mediated vascular regeneration

Z Luo, W Peng, Y Xu, Y Xie, Y Liu, H Lu, Y Cao, J Hu - Acta biomaterialia, 2021 - Elsevier
Vascularization following spinal cord injury (SCI) provides trophic support for rebuilding up
and maintaining the homeostasis of neuronal networks, and the promotion of angiogenesis …