Long-term drug treatment for Restless Legs Syndrome (RLS) patients can frequently result
in augmentation, which is the deterioration of symptoms with an increased drug dose. The …

Virtually all neuropsychiatric disorders display sex differences in prevalence, age of onset,
and/or clinical symptomology. Although altered dopamine (DA) signaling is a feature of …

The social motivation hypothesis of autism proposes that social communication symptoms in
autism-spectrum disorder (ASD) stem from atypical social attention and reward networks …

Zebrafish (Danio rerio) are ideal model organisms for investigating nervous system function,
both in health and disease. Nevertheless, functional characteristics of dopamine (DA) …

Dopamine and serotonin receptors and transporters play an essential role in the
pathophysiology of schizophrenia; changes in their expression have been reported in …

Abstract Dopamine (DA) transporters (DATs) are regulated by trafficking and modulatory
processes that probably rely on stable and transient interactions with neighboring proteins …

Abstract Heat shock cognate 70 (HSC70/HSPA8) is considered to be a promising candidate
gene for schizophrenia (SCZ) due to its many essential functions and potential …

Epilepsy is a widely prevalent disease within the United States. It is estimated that about
1.2% of the total American population has active epilepsy, a condition of the brain that …