Extracellular vesicles in metabolic disease

N Akbar, V Azzimato, RP Choudhury, M Aouadi - Diabetologia, 2019 - Springer
Extracellular vesicles (EVs) are submicron-sized lipid envelopes that are produced and
released from a parent cell and can be taken up by a recipient cell. EVs are capable of …

Platelet-derived extracellular vesicles as target of antiplatelet agents. What is the evidence?

F Taus, A Meneguzzi, M Castelli, P Minuz - Frontiers in pharmacology, 2019 - frontiersin.org
Platelet-derived large extracellular vesicles (often referred to as microparticles in the field of
cardiovascular disease) have been identified as effector in the atherothrombotic process …

Approaches to incorporate extracellular vesicles into exposure science, toxicology, and public health research

CK Carberry, D Keshava, A Payton, GJ Smith… - Journal of exposure …, 2022 - nature.com
Extracellular vesicles (EVs) represent small, membrane-enclosed particles that are derived
from parent cells and are secreted into the extracellular space. Once secreted, EVs can then …

Extracellular vesicles: a novel target for exercise‐mediated reductions in type 2 diabetes and cardiovascular disease risk

NZM Eichner, U Erdbrügger… - Journal of diabetes …, 2018 - Wiley Online Library
Regular exercise is important for reducing type 2 diabetes (T2D) and/or cardiovascular
disease (CVD) risk. However, only about 40–50% of this CVD risk reduction is accounted for …

Impact of short-term exercise training intensity on β-cell function in older obese adults with prediabetes

SK Malin, ME Francois, NZM Eichner… - Journal of applied …, 2018 - journals.physiology.org
The effect of work-matched exercise intensity on β-cell function is unknown in people with
prediabetes before clinical weight loss. We determined if short-term moderate continuous …

Extracellular vesicles in essential hypertension: hidden messengers

S La Salvia, PM Gunasekaran, JB Byrd… - Current Hypertension …, 2020 - Springer
Abstract Purpose of Review Hypertension affects about half of all Americans, yet in the vast
majority of cases, the factors causing the hypertension cannot be clearly delineated …

Postprandial augmentation index is reduced in adults with prediabetes following continuous and interval exercise training

NZM Eichner, JM Gaitán, NM Gilbertson… - Experimental …, 2019 - Wiley Online Library
New Findings What is the central question of this study? We compared high‐intensity
interval versus continuous training on fasting and postprandial arterial stiffness in people …

Two weeks of exercise training intensity on appetite regulation in obese adults with prediabetes

EM Heiston, NZM Eichner… - Journal of applied …, 2019 - journals.physiology.org
No short-term exercise data exist testing whether training intensity modifies hormonal and
perceived appetite in obese adults with prediabetes. Therefore, we compared the effects of …

Insulin infusion decreases medium-sized extracellular vesicles in adults with metabolic syndrome

EM Heiston, A Ballantyne, NR Stewart… - American Journal …, 2022 - journals.physiology.org
Elevated extracellular vesicles (EVs) are associated with glucose dysmetabolism. However,
the effects of insulin on EVs and subsequent relationships with insulin sensitivity, substrate …

Impact of short‐term continuous and interval exercise training on endothelial function and glucose metabolism in prediabetes

SK Malin, NM Gilbertson, NZM Eichner… - Journal of diabetes …, 2019 - Wiley Online Library
Introduction. The impact of interval (INT) vs. continuous (CONT) exercise training on
endothelial function in relation to glucose metabolism prior to clinically meaningful weight …