The renin–angiotensin system is an important component of the cardiovascular system.
Mounting evidence suggests that the metabolic products of angiotensin I and II—initially …

It has been a year since the coronavirus disease 2019 (COVID-19) was declared pandemic
and wreak havoc worldwide. Despite meticulous research has been done in this period …

Vascular injury, characterized by endothelial dysfunction, structural remodelling,
inflammation and fibrosis, plays an important role in cardiovascular diseases. Cellular …

It is well known that the RAS (renin–angiotensin system) plays a key role in the modulation
of many functions in the body. AngII (angiotensin II) acting on AT1R (type 1 AngII receptor) …

ABSTRACT SARS-CoV-2 causes COVID-19, an acute respiratory distress syndrome
(ARDS) characterized by pulmonary edema, viral pneumonia, multiorgan dysfunction …

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the cause of COVID-19, is
reported to increase the rate of mortality worldwide. COVID-19 is associated with acute …

The renin-angiotensin-aldosterone system (RAAS), is an old system with new fundamental
roles in cancer biology which influences cell growth, migration, death, and metastasis. RAAS …

The article describes the rationale for inhibition of the renin-angiotensin system (RAS)
pathways as specific targets in patients infected by SARS-CoV-2 in order to prevent positive …

Besides assisting the maintenance of blood pressure and sodium homeostasis, the renin-
angiotensin system (RAS) plays a pivotal role in pathogenesis of acute kidney injury (AKI) …

Angiotensin-converting enzyme 2 (ACE2) is a membrane-bound protein containing 805
amino acids. ACE2 shows approximately 42% sequence similarity to somatic ACE but has …