The nuclear receptors REV-ERB (consisting of REV-ERBα and REV-ERBβ) and retinoic acid
receptor-related orphan receptors (RORs; consisting of RORα, RORβ and RORγ) are …

Almost 25 centuries ago, Hippocrates, the father of medicine, proclaimed “Let food be thy
medicine and medicine be thy food.” Exploring the association between diet and health …

The ethnopharmacological information gathered over many centuries and the presence of
diverse metabolites have made the medicinal plants as the prime source of drugs. Despite …

The process of tumorigenesis requires cellular transformation, hyperproliferation, invasion,
angiogenesis, and metastasis. Several genes that mediate these processes are regulated …

Covering: up to May 2010 This review (with 335 references cited) is devoted to pentacyclic
triterpenes. The total synthesis, semi-synthesis, structural modification, and metabolic …

Although spices have been used for thousands of years and are known for their flavor, taste
and color in the food, they are not usually recognized for their medicinal value. Extensive …

Extensive research within the last half a century has revealed that cancer is caused by
dysregulation of as many as 500 different gene products. Most natural products target …

AIM: Ursolic acid (UA) and oleanolic acid (OA) are triperpene acids having a similar
chemical structure and are distributed wildly in plants all over the world. In recent years, it …

Purpose: Development of chemoresistance, poor prognosis, and metastasis often renders
the current treatments for colorectal cancer (CRC) ineffective. Whether ursolic acid, a …

Despite the fact cancer is primarily a preventable disease, recent statistics indicate cancer
will become the number one killer worldwide in 2010. Since certain cancers are more …