The SPOT-synthesis technique: synthetic peptide arrays on membrane supports—principles and applications

R Frank - Journal of immunological methods, 2002 - Elsevier
Presented first in 1990 at the 21st European Peptide Symposium in Barcelona, Spain [Frank,
R., Güler, S., Krause, S., Lindenmaier, W., 1991. Facile and rapid 'spot synthesis' of large …

[PDF][PDF] Dimension reduction methods for microarray data: a review

R Aziz, CK Verma, N Srivastava - AIMS Bioeng, 2017 - researchgate.net
Dimension reduction methods for microarray data: a review Page 1 AIMS Bioengineering, 4(2):
179-197. DOI: 10.3934/bioeng.2017.2.179 Received: 27 November 2016 Accepted: 01 …

Use of hexahydrolupulones as antibacterial agents

G McGall, JE Forman - US Patent 6,486,286, 2002 - Google Patents
Provided are functionalized Silicon compounds and methods for their Synthesis and use.
The functionalized Silicon com pounds include at least one activated Silicon group and at …

Array of oligonucleotides on a solid substrate

SPA Fodor, MC Pirrung, JL Read, L Stryer - US Patent 5,445,934, 1995 - Google Patents
[57] ABSTRACT A method and apparatus for preparation of a substrate containing a plurality
of sequences. Photoremovable groups are attached to a surface of a substrate. Selected …

Arrays of materials attached to a substrate

SPA Fodor, L Stryer, JL Read, MC Pirrung - US Patent 5,744,305, 1998 - Google Patents
57 ABSTRACT A synthetic strategy for the creation of large scale chemical diversity. Solid-
phase chemistry, photolabile protecting groups, and photolithography are used to achieve …

Very large scale immobilized polymer synthesis

SPA Fodor, L Stryer, MC Pirrung, JL Read - US Patent 5,424,186, 1995 - Google Patents
[57] ABSTRACT A method for synthesizing oligonucleotides on a solid substrate. The
method provides for the irradiation of a first predefined region of the substrate without …

Single molecule arrays for genetic and chemical analysis

R Drmanac, MJ Callow, S Drmanac, BK Hauser… - US Patent …, 2013 - Google Patents
Random arrays of single molecules are provided for carrying out large scale analyses,
particularly of biomolecules, such as genomic DNA, cDNAs, proteins, and the like. In one …

Method of detecting nucleic acids

SPA Fodor, DW Solas, WJ Dower - US Patent 5,800,992, 1998 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
27496811&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Method and apparatus for conducting an array of chemical reactions on a support surface

TM Brennan - US Patent 5,474,796, 1995 - Google Patents
The invention provides apparatus and methods for making arrays of functionalized binding
sites on a support surface. The invention further provides apparatus and methods for …

Solid phase and combinatorial synthesis of benzodiazepine compounds on a solid support

JA Ellman - US Patent 5,288,514, 1994 - Google Patents
Methods, compositions, and devices for synthesis of therapeutically useful compounds. The
invention provides a rapid approach for combinatorial synthesis and screening of libraries of …