Induced pluripotency: history, mechanisms, and applications

M Stadtfeld, K Hochedlinger - Genes & development, 2010 - genesdev.cshlp.org
The generation of induced pluripotent stem cells (iPSCs) from somatic cells demonstrated
that adult mammalian cells can be reprogrammed to a pluripotent state by the enforced …

Induced pluripotent stem cells—opportunities for disease modelling and drug discovery

M Grskovic, A Javaherian, B Strulovici… - Nature reviews Drug …, 2011 - nature.com
The ability to generate induced pluripotent stem cells (iPSCs) from patients, and an
increasingly refined capacity to differentiate these iPSCs into disease-relevant cell types …

Generation of human induced pluripotent stem cells from urine samples

T Zhou, C Benda, S Dunzinger, Y Huang, JC Ho… - Nature protocols, 2012 - nature.com
Human induced pluripotent stem cells (iPSCs) have been generated with varied efficiencies
from multiple tissues. Yet, acquiring donor cells is, in most instances, an invasive procedure …

iPS cells reprogrammed from human mesenchymal-like stem/progenitor cells of dental tissue origin

X Yan, H Qin, C Qu, RS Tuan, S Shi… - Stem cells and …, 2010 - liebertpub.com
Generation of induced pluripotent stem (iPS) cells holds a great promise for regenerative
medicine and other aspects of clinical applications. Many types of cells have been …

Ascorbic acid enhances the cardiac differentiation of induced pluripotent stem cells through promoting the proliferation of cardiac progenitor cells

N Cao, Z Liu, Z Chen, J Wang, T Chen, X Zhao, Y Ma… - Cell research, 2012 - nature.com
Generation of induced pluripotent stem cells (iPSCs) has opened new avenues for the
investigation of heart diseases, drug screening and potential autologous cardiac …

A novel human induced pluripotent stem cell blood-brain barrier model: Applicability to study antibody-triggered receptor-mediated transcytosis

M Ribecco-Lutkiewicz, C Sodja, J Haukenfrers… - Scientific reports, 2018 - nature.com
We have developed a renewable, scalable and transgene free human blood-brain barrier
model, composed of brain endothelial cells (BECs), generated from human amniotic fluid …

Generation of human induced pluripotent stem cells from umbilical cord matrix and amniotic membrane mesenchymal cells

J Cai, W Li, H Su, D Qin, J Yang, F Zhu, J Xu… - Journal of Biological …, 2010 - ASBMB
The umbilical cord and placenta are extra-embryonic tissues of particular interest for
regenerative medicine. They share an early developmental origin and are a source of vast …

Highly efficient induction and long-term maintenance of multipotent cardiovascular progenitors from human pluripotent stem cells under defined conditions

N Cao, H Liang, J Huang, J Wang, Y Chen, Z Chen… - Cell research, 2013 - nature.com
Cardiovascular progenitor cells (CVPCs) derived from human pluripotent stem cells
(hPSCs), including human embryonic stem cells (hESCs) and human induced pluripotent …

Biological characteristics of stem cells from foetal, cord blood and extraembryonic tissues

H Abdulrazzak, D Moschidou… - Journal of the Royal …, 2010 - royalsocietypublishing.org
Foetal stem cells (FSCs) can be isolated during gestation from many different tissues such
as blood, liver and bone marrow as well as from a variety of extraembryonic tissues such as …

Valproic acid confers functional pluripotency to human amniotic fluid stem cells in a transgene-free approach

D Moschidou, S Mukherjee, MP Blundell, K Drews… - Molecular Therapy, 2012 - cell.com
Induced pluripotent stem cells (iPSCs) with potential for therapeutic applications can be
derived from somatic cells via ectopic expression of a set of limited and defined transcription …