Variants of the SH3 and multiple ankyrin repeat domain 3 (SHANK3) gene, encoding
excitatory postsynaptic core scaffolding proteins, are causally associated with numerous …

This study aimed to explore the relationship between autophagy and synaptic plasticity in
the pathogenesis of vascular dementia (VD). The autophagy inhibitor 3-methyladenine (3 …

Missense variants in Kirrel3 are repeatedly identified as risk factors for autism spectrum
disorder and intellectual disability, but it has not been reported if or how these variants …

Adhesion molecules of the immunoglobulin superfamily (IgSF) are essential for neuronal
synapse development across evolution and control various aspects of synapse formation …

Synapses and neural circuits form with exquisite specificity during brain development to
allow the precise and appropriate flow of neural information. Although this property of …

Objective. To explore the effects of sevoflurane on the latency and error times of the passive
avoidance and levels of PSD‐95 and AMPA receptors in the hippocampus. We evaluated …

Neural circuits balance excitatory and inhibitory activity and disruptions in this balance are
commonly found in neurodevelopmental disorders. Mice lacking the intellectual disability …

Multiple previous studies explored the associations between early life factors and the age at
onset of the depression. However, they only focused on the influence of environmental or …

Kirrel3 is a cell-adhesion molecule that instructs the formation of specific synapses during
brain development in mouse and Kirrel3 variants may be risk factors for autism and …

Kin of irregular chiasm-like 3 (Kirrel3), a member of the immunoglobulin superfamily, is
expressed in the central nervous system during development and in adulthood. It has been …