[HTML][HTML] Translation machinery: the basis of translational control

S Yuan, G Zhou, G Xu - Journal of Genetics and Genomics, 2024 - Elsevier
Messenger RNA (mRNA) translation consists of initiation, elongation, termination, and
ribosome recycling, carried out by the translation machinery, primarily including tRNAs …

RNA editing enzymes: structure, biological functions and applications

D Zhang, L Zhu, Y Gao, Y Wang, P Li - Cell & Bioscience, 2024 - Springer
With the advancement of sequencing technologies and bioinformatics, over than 170
different RNA modifications have been identified. However, only a few of these modifications …

Single-molecule identification of the target RNAs of different RNA binding proteins simultaneously in cells

MN Flamand, K Ke, R Tamming… - Genes & …, 2022 - genesdev.cshlp.org
RNA-binding proteins (RBPs) regulate nearly every aspect of mRNA processing and are
important regulators of gene expression in cells. However, current methods for transcriptome …

Comparison of TRIBE and STAMP for identifying targets of RNA binding proteins in human and Drosophila cells

KC Abruzzi, C Ratner, M Rosbash - Rna, 2023 - rnajournal.cshlp.org
RNA binding proteins (RBPs) perform a myriad of functions and are implicated in numerous
neurological diseases. To identify the targets of RBPs in small numbers of cells, we …

Profiling dynamic RNA–protein interactions using small-molecule-induced RNA editing

KW Seo, RE Kleiner - Nature chemical biology, 2023 - nature.com
RNA-binding proteins (RBPs) play an important role in biology, and characterizing dynamic
RNA–protein interactions is essential for understanding RBP function. In this study, we …

PIE-seq: identifying RNA-binding protein targets by dual RNA-deaminase editing and sequencing

X Ruan, K Hu, X Zhang - Nature Communications, 2023 - nature.com
RNA-binding proteins (RBPs) are essential for gene regulation, but it remains a challenge to
identify their RNA targets across cell types. Here we present PIE-Seq to investigate Protein …

RNA splicing factor RBFOX2 is a key factor in the progression of cancer and cardiomyopathy

J Shen, J Shentu, C Zhong, Q Huang… - Clinical and …, 2024 - Wiley Online Library
Background Alternative splicing of pre‐mRNA is a fundamental regulatory process in
multicellular eukaryotes, significantly contributing to the diversification of the human …

RNA-binding motif protein 28 enhances angiogenesis by improving STAT3 translation in hepatocellular carcinoma

H Han, Y Yuan, C Li, L Liu, H Yu, G Han, Q Wang… - Cancer Letters, 2024 - Elsevier
Hepatocellular carcinoma (HCC) is a prevalent malignant tumor characterized by extensive
angiogenesis. However, the underlying mechanisms of HCC pathogenesis remain unclear …

A transient in planta editing assay identifies specific binding of the splicing regulator PTB as a prerequisite for cassette exon inclusion

J Loeser, J Bauer, K Janßen, K Rockenbach… - Plant Molecular …, 2024 - Springer
The dynamic interaction of RNA-binding proteins (RBPs) with their target RNAs contributes
to the diversity of ribonucleoprotein (RNP) complexes that are involved in a myriad of …

Aberrant APOBEC3C expression induces characteristic genomic instability in pancreatic ductal adenocarcinoma

Y Qian, Y Gong, X Zou, Y Liu, Y Chen, R Wang, Z Dai… - Oncogenesis, 2022 - nature.com
Pancreatic ductal adenocarcinoma (PDAC) is a well-known lethal and heterogeneous
disease. Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like (APOBEC) is an …