Adenovirus is a highly evolutionary successful pathogen, as it is widely prevalent across the
animal kingdom, infecting hosts ranging from lizards and frogs to dolphins, birds, and …

Simple Summary Animal models are widely used to study various aspects of human
diseases and disorders. Likewise, they are indispensable for preclinical testing of medicals …

Oncolytic virus therapy is a cancer treatment modality that has the potential to improve
outcomes for patients with currently incurable malignancies. Although intravascular delivery …

Adenovirus (AdV) is one of the most widely used vectors for gene therapy and vaccine
studies due to its excellent transduction efficiency, capacity for large transgenes, and high …

Gene and cell therapies are widely recognized as future cancer therapeutics but poor
controllability limits their clinical applications. Optogenetics, the use of light-controlled …

To streamline standard virological assays, we developed a suite of nine fluorescent or
bioluminescent replication competent human species C5 adenovirus reporter viruses that …

Viruses are obligate parasites of cellular hosts and therefore are constantly confronted with
the host immune system. Evasion of innate immunity mechanisms by viruses is paramount …

The majority of adenovirus (Ad) vectors are based on human Ad type 5, which is a member
of Ad species C. Species C also includes the closely-related types 1, 2, 6, 57 and 89. It is …

Vectors based on human adenovirus C type 5 (hAdV5/Ad5) are promising candidates for
oncolytic virotherapy due to extensive knowledge of their biology, ease of production at high …

Las enfermedades infecciosas son aquellas causadas por algún tipo de agente infeccioso,
ya sean bacterias, parásitos, hongos o virus. El tratamiento más común para este tipo de …