Inducible Nitric Oxide Synthase/Nitric Oxide System as a Biomarker for Stress and Ease Response in Fish: Implication on Na+ Homeostasis During Hypoxia

MCS Peter, R Gayathry, VS Peter - Frontiers in Physiology, 2022 - frontiersin.org
The cellular and organismal response to stressor-driven stimuli evokes stress response in
vertebrates including fishes. Fishes have evolved varied patterns of stress response …

Are reactive oxygen species always bad? Lessons from hypoxic ectotherms

A Bundgaard, BG Borowiec… - Journal of Experimental …, 2024 - journals.biologists.com
Oxygen (O2) is required for aerobic energy metabolism but can produce reactive oxygen
species (ROS), which are a wide variety of oxidant molecules with a range of biological …

Goldfish response to chronic hypoxia: mitochondrial respiration, fuel preference and energy metabolism

E Farhat, H Cheng, C Romestaing, M Pamenter… - Metabolites, 2021 - mdpi.com
Hypometabolism is a hallmark strategy of hypoxia tolerance. To identify potential
mechanisms of metabolic suppression, we have used the goldfish to quantify the effects of …

Combined effects of salinity and intermittent hypoxia on mitochondrial capacity and reactive oxygen species efflux in the Pacific oyster, Crassostrea gigas

J Steffen, EP Sokolov, C Bock… - Journal of …, 2023 - journals.biologists.com
Coastal environments commonly experience fluctuations in salinity and hypoxia–
reoxygenation (H/R) stress that can negatively affect mitochondrial functions of marine …

Research on sablefish (Anoplopoma fimbria) suggests that limited capacity to increase heart function leaves hypoxic fish susceptible to heat waves

RHJ Leeuwis, FS Zanuzzo… - Proceedings of the …, 2021 - royalsocietypublishing.org
Studies of heart function and metabolism have been used to predict the impact of global
warming on fish survival and distribution, and their susceptibility to acute and chronic …

Acclimation to warm temperatures has important implications for mitochondrial function in Atlantic salmon (Salmo salar)

L Gerber, KA Clow, AK Gamperl - Journal of Experimental …, 2021 - journals.biologists.com
In fish, the capacity of thermal acclimation to preserve cardiac mitochondrial function under
future warming scenarios is important to understand given the central roles that cardiac …

Intrinsic mechanisms underlying hypoxia-tolerant mitochondrial phenotype during hypoxia-reoxygenation stress in a marine facultative anaerobe, the blue mussel …

EP Sokolov, L Adzigbli, S Markert… - Frontiers in Marine …, 2021 - frontiersin.org
Hypoxia is common in marine environments and a major stressor for marine organisms
inhabiting benthic and intertidal zones. Several studies have explored the responses of …

The metabolic fingerprint of doxorubicin-induced cardiotoxicity in male CD-1 mice fades away with time while autophagy increases

SR Brandão, A Reis-Mendes, MJ Neuparth… - Pharmaceuticals, 2023 - mdpi.com
The cardiotoxicity of doxorubicin (DOX) may manifest at the beginning/during treatment or
years after, compromising patients' quality of life. We intended to study the cardiac pathways …

Modulation of mitochondrial site-specific hydrogen peroxide efflux by exogenous stressors

CN Okoye, D Stevens, C Kamunde - Free Radical Biology and Medicine, 2021 - Elsevier
Oxygen (O 2) deprivation and metals are common environmental stressors and their
exposure to aquatic organisms can induce oxidative stress by disrupting cellular reactive …

The role of reversible protein phosphorylation in regulation of the mitochondrial electron transport system during hypoxia and reoxygenation stress in marine bivalves

HI Falfushynska, E Sokolov, H Piontkivska… - Frontiers in Marine …, 2020 - frontiersin.org
Fluctuations in the ambient oxygen concentrations represent a major stressor for aerobic
organisms causing ATP deficiency during hypoxia and excessive production of reactive …