Synthesis of pharmacological relevant 1, 2, 3-triazole and its analogues-A review

R Varala, HB Bollikolla… - Current Organic …, 2021 - ingentaconnect.com
In this review, authors focus mostly on the various synthetic strategies developed so far for 1,
2, 3-triazole scaffold and its derivatives via different approaches such as metal-free, metal …

Triazoles Synthesis & Applications as Nonsteroidal Aromatase Inhibitors for Hormone‐Dependent Breast Cancer Treatment

HRM Rashdan, IA Shehadi - Heteroatom Chemistry, 2022 - Wiley Online Library
In the last few years, nonsteroidal aromatase inhibitors (AIs) have been emerged as
promising agents for treating hormone‐dependent breast cancer in postmenopausal women …

Metal-free syntheses of N-functionalized and NH-1, 2, 3-triazoles: an update on recent developments

T Opsomer, W Dehaen - Chemical Communications, 2021 - pubs.rsc.org
An overview of the latest developments in the metal-free synthesis of non-benzo-fused N-
functionalized and NH-1, 2, 3-triazoles is provided in this feature article. Synthetic studies …

4‐(Dimethylamino) Pyridinium Azide in Protic Ionic Liquid Media as a Stable Equivalent of Hydrazoic Acid

IA Andreev, MA Boichenko… - Advanced Synthesis …, 2022 - Wiley Online Library
We report a procedure for the multigram synthesis of 4‐(dimethylamino) pyridinium azide, a
stable, non‐explosive, low‐hygroscopic source of azide ion soluble in both protic and …

Efficient synthesis of diverse 5-thio-or 5-selenotriazoles: One-pot multicomponent reaction from elemental sulfur or selenium

LL Zhang, YT Li, T Gao, SS Guo, B Yang, ZH Meng… - …, 2019 - thieme-connect.com
A sequential multistep reaction toward 5-thio-or 5-selenotriazoles has been established by
generation of both copper (I) triazolides and sulfenylating or selenylating agents in situ …

Synthesis of 2,1-Benzoisoxazole-Containing 1,2,3-Triazoles through Copper-Catalyzed Three-Component Domino Reactions of o-Bromoacetophenones, Aldehydes …

Y Wang, P Yu, Q Ren, F Jia, Y Chen… - The Journal of Organic …, 2020 - ACS Publications
We herein describe an efficient copper-catalyzed three-component domino protocol used to
prepare 2, 1-benzoisoxazole-containing 1, 2, 3-triazoles from commercially available o …

Progress in synthetic trends followed for the development of 1, 2, 3-triazole derivatives: a review

MM Masood - Polycyclic Aromatic Compounds, 2024 - Taylor & Francis
Since the beginning of click chemistry, 1, 2, 3-triazoles has been at the center of modern
organic chemistry. This versatile framework has found broad applications in organic …

Niacin as a Potent Organocatalyst towards the Synthesis of Quinazolines Using Nitriles as C–N Source

R Gujjarappa, N Vodnala, VG Reddy… - European Journal of …, 2020 - Wiley Online Library
An efficient and cost‐effective Vitamin‐B3‐catalyzed protocol towards the synthesis of
diversely substituted quinazolines is illustrated using 2‐aminobenzylamines and nitriles as …

Organocatalytic Decarboxylation and Dual C(sp3)−H Bond Functionalization Toward Facile Access to Divergent 2,6‐Diarylpyridines

R Gujjarappa, N Vodnala, D Musib… - Asian Journal of …, 2022 - Wiley Online Library
An effective organocatalytic protocol toward the assembly of symmetrical and unsymmetrical
2, 6‐diarylpyridines is demonstrated. The reaction proceeds through organocatalytic …

[HTML][HTML] Potassium tert-Butoxide Promoted Synthesis of 4, 5-Diaryl-2H-1, 2, 3-triazoles from Tosylhydrazones and Nitriles

S Qiu, Y Chen, X Song, L Liu, X Liu, L Wu - Synlett, 2021 - thieme-connect.com
Intermolecular cycloaddition of tosylhydrazones with nitriles was investigated. t-BuOK was
shown to be an excellent base for increasing the effectiveness of the reaction in this …