Senescent cell accumulation has been observed in age-associated diseases including
cardiovascular diseases. Senescent cells lack proliferative capacity and secrete senescence …

Obesity is a worldwide trend that is growing in incidence very fast. Adipose tissue
dysfunction caused by obesity is associated with the generation of oxidative stress. Obesity …

NAD+-dependent deacetylase sirtuin-1 (Sirt1) belongs to the sirtuins family, known to be
longevity regulators, and exerts a key role in the prevention of vascular aging. By aging, the …

Objective In this article, we review the articles that have reported the interaction between
Klotho and sirtuins. Recent findings Sirtuins are a family of histone deacetylase enzymes …

Endothelial cell dysfunction contributes to age-related vascular diseases. Analyzing public
databases and mouse tissues, we found decreased MFN2 expression in senescent …

Introduction: Kidney stones (KSs) are associated with hematuria and renal failure and pose
a significant clinical and public health concern. Diabetes is associated with a higher risk of …

Atherosclerosis (AS) is a chronic inflammatory disease that is a major cause of
cardiovascular diseases (CVDs), including coronary artery disease, hypertension …

Cardiovascular disease is currently the largest cause of mortality and disability globally,
surpassing communicable diseases, and atherosclerosis is the main contributor to this …

Baicalin is a flavonoid glycoside obtained from the dried root of Scutellaria baicalensis
Georgi, which belongs to the Labiatae family. Accumulating evidence indicates that baicalin …

Ethnopharmacological relevance Vascular endothelial cell senescence is associated with
cardiovascular complications in diabetes. Essential oil from Fructus Alpiniae zerumbet …