Importance Down syndrome is the most common chromosomal condition, and average life
expectancy has increased substantially, from 25 years in 1983 to 60 years in 2020. Despite …

Adults with Down syndrome (DS) represent a unique population who are in need of clinical
guidelines to address their medical care. The United States Preventive Service Task Force …

A recent study has discovered that mesenchymal stem cells (MSCs) are recruited into
tumors and MSC‐derived exosomes in a novel mechanism of cell‐to‐cell communication in …

Endocrine manifestations of Down syndrome : Current Opinion in Endocrinology, Diabetes
and Obesity Endocrine manifestations of Down syndrome : Current Opinion in …

This study analyzed data of bone mineral density (BMD) from a large cohort of adults with
Down syndrome (DS). BMD was found to decrease with age more rapidly in these subjects …

The best available evidence indicates that the most common endogenous pathologic cause
of hypogonadism is Klinefelter syndrome (affecting up to∼ 0.2% of the male population) …

Introduction: In the last decades, life expectancy of persons with Down syndrome (DS) has
dramatically increased and it is estimated that they will be living as long as the general …

Down's syndrome results from increased genetic material on all or a portion of chromosome
21 and is characterized by intellectual disability and risk for comorbidities involving multiple …

Down syndrome (DS) is the most common genetic disorder in live-born infants. Children with
DS are at increased risk of numerous endocrinal comorbidities. The information contained in …

Trisomy 21 causes skeletal alterations in individuals with Down syndrome (DS), but the
causative trisomic gene and a therapeutic approach to rescue these abnormalities are …