From in vitro to in vivo Models of Bacterial Biofilm-Related Infections

D Lebeaux, A Chauhan, O Rendueles, C Beloin - Pathogens, 2013 - mdpi.com
The influence of microorganisms growing as sessile communities in a large number of
human infections has been extensively studied and recognized for 30–40 years, therefore …

Chemotaxis in cancer

ET Roussos, JS Condeelis, A Patsialou - Nature Reviews Cancer, 2011 - nature.com
Chemotaxis of tumour cells and stromal cells in the surrounding microenvironment is an
essential component of tumour dissemination during progression and metastasis. This …

Meet the neighbors: Mapping local protein interactomes by proximity‐dependent labeling with BioID

R Varnaitė, SA MacNeill - Proteomics, 2016 - Wiley Online Library
Proximity‐dependent biotin identification (BioID) is a recently developed method that allows
the identification of proteins in the close vicinity of a protein of interest in living cells. BioID …

Non-Gaussian displacements in active transport on a carpet of motile cells

R Großmann, LS Bort, T Moldenhawer, M Stange… - Physical Review Letters, 2024 - APS
We study the dynamics of micron-sized particles on a layer of motile cells. This cell carpet
acts as an active bath that propels passive tracer particles via direct mechanical contact. The …

Reactive oxygen species in the signaling and adaptation of multicellular microbial communities

M Čáp, L Váchová, Z Palková - Oxidative medicine and cellular …, 2012 - Wiley Online Library
One of the universal traits of microorganisms is their ability to form multicellular structures,
the cells of which differentiate and communicate via various signaling molecules. Reactive …

[HTML][HTML] A Ras signaling complex controls the RasC-TORC2 pathway and directed cell migration

PG Charest, Z Shen, A Lakoduk, AT Sasaki, SP Briggs… - Developmental cell, 2010 - cell.com
Ras was found to regulate Dictyostelium chemotaxis, but the mechanisms that spatially and
temporally control Ras activity during chemotaxis remain largely unknown. We report the …

Chemistry and the Worm: Caenorhabditis elegans as a Platform for Integrating Chemical and Biological Research

SE Hulme, GM Whitesides - Angewandte Chemie International …, 2011 - Wiley Online Library
This Review discusses the potential usefulness of the worm Caenorhabditis elegans as a
model organism for chemists interested in studying living systems. C. elegans, a 1 mm long …

The rise of pathogens: predation as a factor driving the evolution of human pathogens in the environment

M Erken, C Lutz, D McDougald - Microbial ecology, 2013 - Springer
Bacteria in the environment must survive predation from bacteriophage, heterotrophic
protists, and predatory bacteria. This selective pressure has resulted in the evolution of a …

General trends in trace element utilization revealed by comparative genomic analyses of Co, Cu, Mo, Ni, and Se

Y Zhang, VN Gladyshev - Journal of Biological Chemistry, 2010 - ASBMB
Trace elements are used by all organisms and provide proteins with unique coordination
and catalytic and electron transfer properties. Although many trace element-containing …

Simple system–substantial share: the use of Dictyostelium in cell biology and molecular medicine

A Müller-Taubenberger, A Kortholt… - European journal of cell …, 2013 - Elsevier
Dictyostelium discoideum offers unique advantages for studying fundamental cellular
processes, host–pathogen interactions as well as the molecular causes of human diseases …