Manganese-enhanced magnetic resonance imaging (MEMRI) relies on the strong
paramagnetism of Mn2+. Mn2+ is a calcium ion analog and can enter excitable cells through …

Cell transplantation has been studied extensively as a therapeutic strategy for neurological
disorders. However, to date, its effectiveness remains unsatisfactory due to low precision …

Background Currently available therapies for neuropathic pain show limited efficacy. This
study aimed to investigate the anti‐nociceptive effect of the spirocyclopiperazinium salt …

Recent studies have shown the 5-HT 6 receptors are expressed in regions which are
important in pain processing such as the cortex, amygdala, thalamus, PAG, spinal cord and …

Introduction The vagus nerve, the primary neural pathway mediating brain-body interactions,
plays an essential role in transmitting bodily signals to the brain. Despite its significance, our …

Although it is known that nociceptive stimulation in the first postnatal week in rats is useful to
model preterm pain, resulting in activation of specific brain areas, as assessed in vivo using …

Neuropathic pain induced by a nerve injury can lead to chronic pain. Recent studies have
reported hyperactive neural activities in the nociceptive-related area of the brain as a result …

目的对比分析不同致痒剂诱导大鼠瘙痒模型的效果. 方法选择3~ 4 月龄健康雄性SD 大鼠240 只,
分为组胺依赖性致痒剂(磷酸组胺组, 化合物48/80 组) 和非组胺依赖性致痒剂(5-羟色胺组 …

Background The spinal cord is composed of nine distinct cellular laminae that currently can
only be visualized by histological methods. Developing imaging methods that can visualize …

Abstract Manganese Enhanced MRI (MEMRI) utilizing different manganese chloride
(MnCl2) delivery methods, has yielded valuable architectural, functional and connection …