Engineered exosomes from different sources for cancer-targeted therapy
M Zhang, S Hu, L Liu, P Dang, Y Liu, Z Sun… - Signal transduction and …, 2023 - nature.com
Exosome is a subgroup of extracellular vesicles, which has been serving as an efficient
therapeutic tool for various diseases. Engineered exosomes are the sort of exosomes …
therapeutic tool for various diseases. Engineered exosomes are the sort of exosomes …
Advances in drug delivery systems based on red blood cells and their membrane-derived nanoparticles
Red blood cells (RBCs) and RBC membrane-derived nanoparticles have been historically
developed as bioinspired drug delivery systems to combat the issues of premature …
developed as bioinspired drug delivery systems to combat the issues of premature …
Homologous cancer cell membrane-camouflaged nanoparticles target drug delivery and enhance the chemotherapy efficacy of hepatocellular carcinoma
Y Wu, R Zhu, M Zhou, J Liu, K Dong, S Zhao, J Cao… - Cancer letters, 2023 - Elsevier
Hepatocellular carcinoma (HCC) is a common digestive tract malignancy that seriously
threatens human life and health. Early HCC may be treated by intervention, surgery, and …
threatens human life and health. Early HCC may be treated by intervention, surgery, and …
Red blood cell-derived extracellular vesicles display endogenous antiviral effects and enhance the efficacy of antiviral oligonucleotide therapy
The COVID-19 pandemic has resulted in a large number of fatalities and, at present, lacks a
readily available curative treatment for patients. Here, we demonstrate that unmodified red …
readily available curative treatment for patients. Here, we demonstrate that unmodified red …
Endocytosis of red blood cell extracellular vesicles by macrophages leads to cytoplasmic heme release and prevents foam cell formation in atherosclerosis
Extracellular vesicles (EVs) can be produced from red blood cells (RBCs) on a large scale
and used to deliver therapeutic payloads efficiently. However, not much is known about the …
and used to deliver therapeutic payloads efficiently. However, not much is known about the …
Extracellular vesicles as new players in drug delivery: a focus on red blood cells-derived EVs
The article is divided into several sections, focusing on extracellular vesicles'(EVs) nature,
features, commonly employed methodologies and strategies for their isolation/preparation …
features, commonly employed methodologies and strategies for their isolation/preparation …
Landscape of exosomes to modified exosomes: a state of the art in cancer therapy
Exosomes are a subpopulation of extracellular vesicles (EVs) that naturally originate from
endosomes. They play a significant role in cellular communication. Tumor-secreted …
endosomes. They play a significant role in cellular communication. Tumor-secreted …
[HTML][HTML] Endosomal escape of nucleic acids from extracellular vesicles mediates functional therapeutic delivery
Extracellular vesicles hold great promise as a drug delivery platform for RNA-based
therapeutics. However, there is a lack of experimental evidence for the intracellular …
therapeutics. However, there is a lack of experimental evidence for the intracellular …
Recent advances in bacteria-based cancer treatment
X Wei, M Du, Z Chen, Z Yuan - Cancers, 2022 - mdpi.com
Simple Summary Cancer refers to a disease involving abnormal cells that proliferate
uncontrollably and can invade normal body tissue. It was estimated that at least 9 million …
uncontrollably and can invade normal body tissue. It was estimated that at least 9 million …
[HTML][HTML] Red blood cell-derived materials for cancer therapy: construction, distribution, and applications
J Ding, X Ding, W Liao, Z Lu - Materials Today Bio, 2024 - Elsevier
Cancer has become an increasingly important public health issue owing to its high morbidity
and mortality rates. Although traditional treatment methods are relatively effective, they have …
and mortality rates. Although traditional treatment methods are relatively effective, they have …