Astrocytes and microglia are central players in a myriad of processes in the healthy and
diseased brain, ranging from metabolism to immunity. The crosstalk between these two cell …

Microglia are resident immune cells of the central nervous system (CNS) with multiple
functions in health and disease. Their response during encephalitis depends on whether …

INTRODUCTION Glial cells of the central nervous system (CNS), including astrocytes and
microglia, play critical roles in development, tissue repair, and homeostasis. However …

Engineered variants of recombinant adeno-associated viruses (rAAVs) are being developed
rapidly to meet the need for gene-therapy delivery vehicles with particular cell-type and …

Natural killer (NK) cells belong to type 1 innate lymphoid cells (ILC1) and are essential in
killing infected or transformed cells. NK cells mediate their effector functions using non …

Liraglutide and other glucagon-like peptide 1 receptor agonists (GLP-1RAs) are effective
weight loss drugs, but how they suppress appetite remains unclear. One potential …

Cortical circuit tracing using modified rabies virus can identify input neurons making direct
monosynaptic connections onto neurons of interest. However, challenges remain in our …

Innate social behaviours, such as mating and fighting, are fundamental to animal
reproduction and survival. However, social engagements can also put an individual at risk …

An exciting frontier in circuit neuroscience lies at the intersection between neural network
mapping and single-cell genomics. Monosynaptic rabies viruses provide a promising …

Many viral infections cause acute and chronic neurologic diseases which can lead to
degeneration of cortical functions. While neurotropic viruses that gain access to the central …