Beyond chemicals: Opportunities and challenges of integrating non-chemical stressors in adverse outcome pathways

LA Clerbaux, J Filipovska, P Nymark, V Chauhan… - Altex, 2024 - repositorio.ucp.pt
The adverse outcome pathways (AOPs) were developed to accelerate evidence-based
chemical risk assessment by leveraging data from new approach methodologies. Thanks to …

Review of new approach methodologies for application in risk assessment of nanoparticles in the food and feed sector: Status and challenges

SM Usmani, S Bremer‐Hoffmann… - EFSA Supporting …, 2024 - Wiley Online Library
Abstract New Approach Methodologies (NAMs), broadly understood to include in silico, in
chemico, in vitro and ex vivo methods, show great potential in advancing risk assessment …

An Adverse Outcome Pathway for food nanomaterial-induced intestinal barrier disruption

D Stanco, D Lipsa, A Bogni… - Frontiers in …, 2024 - frontiersin.org
Introduction The ingestion of nanomaterials (NMs) may impair the intestinal barrier, but the
underlying mechanisms remain evasive, and evidence has not been systematically …