New horizons in adjuvants for vaccine development

SG Reed, S Bertholet, RN Coler, M Friede - Trends in immunology, 2009 - cell.com
Over the last decade, there has been a flurry of research on adjuvants for vaccines, and
several novel adjuvants are now in licensed products or in late stage clinical development …

Malaria vaccines: progress to date

DI Stanisic, MF Good - BioDrugs, 2023 - Springer
Malaria is a mosquito-borne disease caused by protozoan parasites of the genus
Plasmodium. Despite significant declines in malaria-attributable morbidity and mortality over …

Recent progress in adjuvant discovery for peptide-based subunit vaccines

F Azmi, AAH Ahmad Fuaad… - Human vaccines & …, 2014 - Taylor & Francis
Peptide-based subunit vaccines are of great interest in modern immunotherapy as they are
safe, easy to produce and well defined. However, peptide antigens produce a relatively …

Malaria in school‐age children in A frica: an increasingly important challenge

J Nankabirwa, SJ Brooker, SE Clarke… - Tropical medicine & …, 2014 - Wiley Online Library
School‐age children have attracted relatively little attention as a group in need of special
measures to protect them against malaria. However, increasing success in lowering the …

Duration of protection with RTS, S/AS02A malaria vaccine in prevention of Plasmodium falciparum disease in Mozambican children: single-blind extended follow-up of …

PL Alonso, J Sacarlal, JJ Aponte, A Leach, E Macete… - The Lancet, 2005 - thelancet.com
Summary Background RTS, S/AS02A is a pre-erythrocytic stage malaria vaccine that
provides partial protection against infection in malaria-naive adult volunteers and …

The future for blood‐stage vaccines against malaria

JS Richards, JG Beeson - Immunology and cell biology, 2009 - Wiley Online Library
Malaria is a leading cause of mortality and morbidity globally, and effective vaccines are
urgently needed. Malaria vaccine approaches can be broadly grouped as pre‐erythrocytic …

The RTS, S malaria vaccine

S Casares, TD Brumeanu, TL Richie - Vaccine, 2010 - Elsevier
RTS, S is the most advanced candidate vaccine against human malaria. During its
remarkable journey from conception and design in the early 1980s to the multicenter Phase …

Plasmodium falciparum Malaria Vaccines and Vaccine Adjuvants

SR Bonam, L Rénia, G Tadepalli, J Bayry, HMS Kumar - Vaccines, 2021 - mdpi.com
Malaria—a parasite vector-borne disease—is a global health problem, and Plasmodium
falciparum has proven to be the deadliest among Plasmodium spp., which causes malaria in …

A review of human vaccine research and development: malaria

MP Girard, ZH Reed, M Friede, MP Kieny - Vaccine, 2007 - Elsevier
The last several years have seen significant progress in the development of vaccines
against malaria. Most recently, proof-of-concept of vaccine-induced protection from malaria …

Plasmodium falciparum pre-erythrocytic stage vaccine development

J Molina-Franky, L Cuy-Chaparro, A Camargo… - Malaria journal, 2020 - Springer
Worldwide strategies between 2010 and 2017 aimed at controlling malarial parasites
(mainly Plasmodium falciparum) led to a reduction of just 18% regarding disease incidence …