Advances in stroke pharmacology

Z Zhou, J Lu, WW Liu, A Manaenko, X Hou… - Pharmacology & …, 2018 - Elsevier
Stroke occurs when a cerebral blood vessel is blocked or ruptured, and it is the major cause
of death and adult disability worldwide. Various pharmacological agents have been …

Why to study peptides from venomous and poisonous animals?

AN de Oliveira, AM Soares, SL Da Silva - International Journal of Peptide …, 2023 - Springer
Venom and poison peptides are powerful biological weapons and have proven immense
pharmacological potential because of their high binding affinity to a wide range of molecular …

Random forest-based prediction of stroke outcome

C Fernandez-Lozano, P Hervella, V Mato-Abad… - Scientific reports, 2021 - nature.com
We research into the clinical, biochemical and neuroimaging factors associated with the
outcome of stroke patients to generate a predictive model using machine learning …

Effects of telestroke on thrombolysis times and outcomes: a meta-analysis

A Baratloo, L Rahimpour, AI Abushouk… - Prehospital …, 2018 - Taylor & Francis
Objective: Telestroke systems are tools, used to provide an advanced stroke care in regions
without sufficient neurologic services. We performed this meta-analysis to assess the effects …

Trends in stroke outcomes in the last ten years in a European tertiary hospital

E Rodriguez-Castro, I Lopez-Dequit… - BMC neurology, 2018 - Springer
Background Studying the impact of demographic changes and progress in the management
of stroke patients is necessary in order to organize care structures for the coming years …

Efficacy and safety of thrombolysis for acute ischemic stroke with atrial fibrillation: a meta-analysis

Y Hu, C Ji - BMC neurology, 2021 - Springer
Background The efficacy and safety of intravenous thrombolysis (IVT) for acute ischemic
stroke with atrial fibrillation (AF) is still controversial. Methods We conducted a meta-analysis …

Silver jubilee of stroke thrombolysis with alteplase: evolution of the therapeutic window

Y Pan, G Shi - Frontiers in Neurology, 2021 - frontiersin.org
In 1995, the results of a landmark clinical trial by National Institute of Neurological Disorders
and Stroke (NINDS) made a paradigm shift in managing acute cerebral ischemic stroke …

Efficacy and safety of desmoteplase in acute ischemic stroke patients: a systematic review and meta-analysis

X Li, L Ling, C Li, Q Ma - Medicine, 2017 - journals.lww.com
Background: Pending results from double-blind, multicenter, parallel-group, randomized
trials, the benefit and safety of the novel plasminogen activator, desmoteplase remain …

The use of intravenous thrombolytics in acute ischemic stroke management: a scoping review from 2008 till 2021 in the Arab world in the Middle East and North Africa

D Malaeb, S Hallit, F Sakr, M Dabbous… - Journal of Stroke and …, 2023 - Elsevier
Objective The aim of this review was to assess and analyze the research output on
intravenous thrombolysis in acute ischemic stroke in the Arab world in the Middle East and …

Modulation of the mammalian coagulation system by venoms and other proteins from snakes, arthropods, nematodes and insects

ATA Sachetto, N Mackman - Thrombosis Research, 2019 - Elsevier
The mammalian hemostatic system involves complex interactions between protein
components of the coagulation cascade and platelets. The fibrinolytic system removes the …