Cytokines related to tumor necrosis factor (TNF) provide a communication network essential
for coordinating multiple cell types into an effective host defense system against pathogens …

CD30 is a member of the tumor necrosis factor receptor superfamily. It is characteristically
expressed in certain hematopoietic malignancies, including anaplastic large cell lymphoma …

Membranous Nephropathy (MN) is a rare autoimmune cause of kidney failure. Here we
report a genome-wide association study (GWAS) for primary MN in 3,782 cases and 9,038 …

Peripheral T cell lymphomas (PTCLs) are a heterogeneous group of orphan neoplasms.
Despite the introduction of anthracycline-based chemotherapy protocols, with or without …

The understanding of the impact of the non-canonical NF-κB (nuclear factor kappa-light-
chain-enhancer of activated B cells) pathway in several human diseases including …

Peripheral T-cell lymphomas (PTCLs) represent a heterogeneous group of T-cell
malignancies that generally demonstrate aggressive clinical behavior, often are refractory to …

After exiting the thymus, Foxp3+ regulatory T (Treg) cells undergo further differentiation in
the periphery, resulting in the generation of mature, fully suppressive effector (e) Treg cells …

T-and NK-cell lymphomas (TCL) are a heterogenous group of lymphoid malignancies with
poor prognosis. In contrast to B-cell and myeloid malignancies, there are few preclinical …

Anaplastic large cell lymphomas (ALCLs) represent a relatively common group of T-cell non-
Hodgkin lymphomas (T-NHLs) that are unified by similar pathologic features but …

The success of programmed cell death protein 1 (PD-1)/PD-L1-based immunotherapy
highlights the critical role played by PD-L1 in cancer progression and reveals an urgent …