Background Gut microbiota dysbiosis and sarcopenia commonly occur in the elderly.
Although the concept of the gut–muscle axis has been raised, the casual relationship is still …

Chronic kidney disease (CKD) afflicts more than 500 million people worldwide and is one of
the fastest growing global causes of mortality. When glomerular filtration rate begins to fall …

Chronic kidney disease (CKD) causes progressive skeletal myopathy involving atrophy,
weakness, and fatigue. Mitochondria have been thought to contribute to skeletal myopathy; …

Sarcopenia is characterized by a progressive loss of skeletal muscle mass and function with
aging. Recently, sarcopenia has been shown to be closely related with gut microbiota …

Uremic sarcopenia is a frequent condition present in chronic kidney disease (CKD) patients
and is characterized by reduced muscle mass, muscle strength and physical performance …

Preclinical animal models of chronic kidney disease (CKD) are critical to investigate the
underlying mechanisms of disease and to evaluate the efficacy of novel therapeutics aimed …

Skeletal muscle is one of the largest organs in the body and is essential for maintaining
quality of life. Loss of skeletal muscle mass and function can lead to a range of adverse …

The maintenance of functional independence is the top priority of patients with chronic
kidney disease (CKD). Defects in mitochondrial energetics may compromise physical …

Kidney diseases have become one of the most common health care problems. Due to a
growing number of advanced aged patients with concomitant disorders the prevalence of …

Ageing is a complex process that is associated with changes in the composition and
functions of gut microbiota. Reduction of gut commensals is the hallmarks of ageing, which …