Protein/antibody therapeutics have exhibited the advantages of high specificity and activity
even at an extremely low concentration compared to small molecule drugs. However, they …

Insulin is essential for type 1 and advanced type 2 diabetics to maintain blood glucose levels
and prolong lives. The traditional administration requires frequent subcutaneous insulin …

Nanoparticles have demonstrated significant advancements in potential oral delivery of
insulin. In this publication, we review the current status of polymeric, inorganic and solid-lipid …

Diabetes mellitus, an incurable metabolic disease, is characterized by changes in the
homeostasis of blood sugar levels, being the subcutaneous injection of insulin the first line …

The penetration of polar or badly soluble compounds through a cell membrane into live cells
requires mechanical support or chemical helpers. Cell‐penetrating peptides (CPPs) are very …

Diabetes mellitus is a high prevalence and one of the most severe and lethal diseases in the
world. Insulin is commonly used to treat diabetes in order to give patients a better life …

Diabetes mellitus (DM) is a chronic metabolic illness estimated to have affected 451 million
individuals to date, with this number expected to significantly rise in the coming years. There …

The therapeutic efficacy of orally administered drugs is often restricted by their inherent
limited oral bioavailability. Low water solubility, limited permeability through the intestinal …

Cell‐penetrating peptides (CPPs) can transport various cargoes through membranes of live
cells. Since the first generations of CPPs suffered from insufficient cell and tissue selectivity …

In this study, the collagen/chitosan gel composite supplemented with a cell-penetrating
peptide (CPP)(Oligoarginine, R8) was prepared. Then, the physicochemical properties of …