Ovarian cancer is the leading cause of gynecological cancer death. Improved understanding
of the biologic pathways and introduction of poly (ADP-ribose) polymerase inhibitors …

This review of the meaningful data from 2021 on cervical, endometrial, and ovarian cancers
aims to provide an update of the most clinically relevant studies presented at important …

Ovarian cancer (OC) is the leading cause of death from gynecological malignancies
worldwide. Fortunately, recent advances in OC biology and the discovery of novel …

BRCA1/2 genes are part of homologous recombination (HR) DNA repair pathways in charge
of error-free double-strand break (DSB) repair. Loss-of-function mutations of BRCA1/2 …

Advanced epithelial ovarian cancer is the commonest cause of gynaecological cancer
deaths. First-line treatment for advanced disease includes a combination of platinum-taxane …

Objective In ovarian cancer (OvCa), tumor cell high glucocorticoid receptor (GR) has been
associated with poor patient prognosis. In vitro, GR activation inhibits chemotherapy …

Cortisol, an endogenous glucocorticoid receptor (GR) agonist, controls a broad
transcriptional program that affects T-cell activation, pro-inflammatory cytokine secretion …

Background: DNA double strand breaks can affect genome integrity potentially leading to
cancer. RAD51-associated protein 1 (RAD51AP1), an accessory protein to RAD51, is critical …

Glucocorticoid receptor can be associated with poor prognosis among a variety of solid
tumors in the absence of other nuclear hormone receptors. Our objective was to characterize …

This review of the meaningful data from 2021 on cervical, endometrial, and ovarian cancers
aims to provide an update of the most clinically relevant studies presented at important …