Plasmodium parasites have a complex life cycle alternating between a mosquito and a
vertebrate host. Following the bite of an Anopheles female mosquito, Plasmodium …

Ca2+ is a ubiquitous intracellular messenger in malaria parasites with important functions in
asexual blood stages responsible for malaria symptoms, the preceding liver‐stage infection …

Malaria infections of mammals are initiated by the transmission of Plasmodium salivary
gland sporozoites during an Anopheles mosquito vector bite. Sporozoites make their way …

For those stricken with malaria, the classic clinical symptoms are caused by the parasite's
cyclic infection of red blood cells. However, this erythrocytic phase of the parasite's life cycle …

Plasmodium sporozoites exhibit a complex infection biology in the mosquito and
mammalian hosts. The sporozoite apical secretory organelles, the micronemes and …

Calcium is a key signalling molecule in apicomplexan parasites and plays an important role
in diverse processes including gliding motility. Gliding is essential for the malaria parasite to …

The apicomplexan parasites Plasmodium spp. are the causative agents of malaria, a
disease that poses a significant global health burden. Plasmodium spp. initiate infection of …

Malaria parasites have evolved a complicated life cycle alternating between two hosts.
Gametocytes are produced in the vertebrate hosts and are obligatory for natural …

The calcium ion (Ca2+) is a ubiquitous second messenger involved in key biological
processes in prokaryotes and eukaryotes. In Plasmodium species, Ca2+ signaling plays a …

The liver stage of the etiological agent of malaria, Plasmodium, is obligatory for successful
infection of its various mammalian hosts. Differentiation of the rod-shaped sporozoites of …