In proteins, the amino acids Phe, Tyr, and especially Trp are frequently involved in π
interactions such as π–π, cation− π, and CH− π bonds. These interactions are often crucial …

The self-recognition and self-assembly of biomolecules are spontaneous processes that
occur in Nature and allow the formation of ordered structures, at the nanoscale or even at …

Amyloidosis, commonly known as amyloid-associated diseases, is characterized by
improperly folded proteins accumulating in tissues and eventually causing organ damage …

Fluorinated amino acids play an important role in the field of peptide and protein
engineering. Although numerous syntheses have been published in recent decades …

Environmental plastic wastes are potential health hazards due to their prevalence as well as
their versatility in initiating physical, chemical, and biological interactions and …

Three peptides comprising mono-, di-, and tri-fluoroethylglycine (MfeGly, DfeGly, and TfeGly)
residues alternating with lysine were digested by readily available proteases (elastase …

The short peptide fragment NFGAIL (IAPf) is a well-known amyloidogenic peptide (22–27),
derived from human islet amyloid polypeptide (hIAPP), whose fibrillar structure is often used …

Advanced peptide-based nanomaterials composed of self-assembling peptides (SAPs) are
of emerging interest in pharmaceutical and biomedical applications. The introduction of …

Substituting the P1 position in bovine pancreatic trypsin inhibitor (BPTI) is known to heavily
influence its inhibitory activity towards serine proteases. Side-chain fluorinated aliphatic …

Amphibian skin secretion is an ideal source of antimicrobial peptides that are difficult to
induce drug resistance to due to their membrane-targeting mechanism as a new treatment …