Schizophrenia during the COVID-19 pandemic
Clinicians should inform and educate their patients on the risks related to SARS-CoV-2
infection and COVID-19 and on the precautions that they should adopt to avoid contagion …
infection and COVID-19 and on the precautions that they should adopt to avoid contagion …
Clozapine therapy and COVID-19: a systematic review of the prevalence rates, health outcomes, hematological markers, and patient perspectives
G Giles, S Varghese, G Shymko, T Nguyen… - Schizophrenia …, 2023 - academic.oup.com
Abstract Background/Objectives There have been concerns that clozapine treatment may
undermine the capacity of the body to fight infection and increase the vulnerability to …
undermine the capacity of the body to fight infection and increase the vulnerability to …
[HTML][HTML] Elevated clozapine levels and toxic effects after SARS-CoV-2 vaccination
D Thompson, CM Delorme, RF White… - Journal of Psychiatry and …, 2021 - jpn.ca
Case studies indicate that coronavirus disease 2019 (COVID-19) can be associated with
toxic clozapine levels, requiring monitoring to maintain therapeutic levels and prevent …
toxic clozapine levels, requiring monitoring to maintain therapeutic levels and prevent …
COVID-19: risks, complications, and monitoring in patients on clozapine
SRT Veerman, JPAM Bogers, D Cohen… - …, 2022 - thieme-connect.com
The Dutch Clozapine Collaboration Group is frequently asked for advice about the
management of clozapine-treated patients when infected with or vaccinated against SARS …
management of clozapine-treated patients when infected with or vaccinated against SARS …
[HTML][HTML] Toxicity of psychotropic drugs in patients with COVID-19: a systematic review
Objective Due to the global spread of severe acute respiratory syndrome coronavirus-2
(SARS-CoV-2), guidance for the use of psychotropic drugs in this context is necessary. We …
(SARS-CoV-2), guidance for the use of psychotropic drugs in this context is necessary. We …
[HTML][HTML] Clozapine, neutropenia and Covid-19: should clinicians be concerned? 3 months report
S Bonaccorso, A Ricciardi, S Ouabbou… - Brain, Behavior, & …, 2021 - Elsevier
Background Clozapine is among the most effective antipsychotics used for treatment
resistant schizophrenia. Adverse reactions to clozapine include neutropenia. In March 2020 …
resistant schizophrenia. Adverse reactions to clozapine include neutropenia. In March 2020 …
[HTML][HTML] A Covid-19 outbreak in a Spanish long-term psychiatric hospital led to infections in 6 clozapine patients: elevations in their plasma clozapine levels
M Arrojo-Romero, MR Codesido-Barcala… - Revista de psiquiatria …, 2022 - ncbi.nlm.nih.gov
Clozapine is mainly metabolized by the cytochrome P450 1A2 (CYP1A2) leading to its main
metabolite, norclozapine. 1 Clozapine metabolism is influenced by 3 levels of complexity:(1) …
metabolite, norclozapine. 1 Clozapine metabolism is influenced by 3 levels of complexity:(1) …
Neutropenia after the coadministration of clozapine and nirmatrelvir-ritonavir in a patient with SARS-CoV-2 infection: A case report with a literature review
CI Liu, KK Goh, CH Chen - Frontiers in Psychiatry, 2022 - frontiersin.org
Background Schizophrenia is considered one of the major risk factors for mortality from
SARS-CoV-2 infection. Early antiviral treatment is important to decrease the risk of mortality …
SARS-CoV-2 infection. Early antiviral treatment is important to decrease the risk of mortality …
[HTML][HTML] COVID-related hospitalization, intensive care treatment, and all-cause mortality in patients with psychosis and treated with clozapine
R Govind, DF de Freitas, M Pritchard… - European …, 2022 - Elsevier
Clozapine, an antipsychotic, is associated with increased susceptibility to infection with
COVID-19, compared to other antipsychotics. Here, we investigate associations between …
COVID-19, compared to other antipsychotics. Here, we investigate associations between …
Neutropenia in patients with clozapine-treated schizophrenia: an effect of clozapine or a consequence of SARS-CoV-2 infection? A Systematic Review
S Moga, A Teodorescu, A Dragan… - American Journal of …, 2022 - journals.lww.com
Background: Clozapine is the only approved antipsychotic for treatment-resistant
schizophrenia. Despite its therapeutic benefits, it is still widely underused, mainly because of …
schizophrenia. Despite its therapeutic benefits, it is still widely underused, mainly because of …