Enzymes are the biological macromolecules that have emerged as an important drug target
as their upregulation/imbalance leads to various pathological conditions, such as …

The reaction of variously substituted 1, 2, 4-triazole derivatives with morpholine and
formaldehyde represents an efficient and easy-to-set synthetic entry toward heterocyclic N …

The novel benzothiazole sulfonate hybrid derivatives containing azomethine group were
synthesized and characterized using 1H‐NMR, 13C‐NMR, and HR‐MS analysis. The …

Obesity, characterized by excessive fat accumulation, is a major health concern. Inhibition of
human pancreatic lipase, an enzyme involved in fat digestion, offers a potential strategy for …

This paper provides a comprehensive account of the synthesis and assessment of newly
developed aryl sulfonate derivatives based on benzothiazole as enzyme inhibitors …

A series of new Schiff bases of semicarbazones and thiosemicarbazones have been derived
from the condensation of symmetrical chalcones with semicarbazide and thiosemicarbazide …

Small molecule multi-target drugs substituted with fluorine atom/s or fluorine-containing
group/s continue to attract considerable interest in medicinal chemistry due to their …

Lipase inhibitors are used in the treatment of candidiasis, obesity, and acne problems.
Therefore, the investigation of new natural lipase inhibitors has generated great interest …

We have synthesized a novel library of benzofuran-derived thiadiazole/oxadiazole-based
thiourea derivatives (1-28) targeting one of the rising health issues all over the world …

Phenylpropanoids (PPs), a group of natural compounds characterized by one or more C6-
C3 units, have exhibited considerable potential in addressing metabolic disease. However …