Leishmania is an obligate intracellular pathogen that invades phagocytic host cells.
Approximately 30 different species of Phlebotomine sand flies can transmit this parasite …

Leishmaniasis is a tropical disease caused by an intracellular parasite of the genus
Leishmania. The vector of transmission is the sandfly, which deposits one of the 20 disease …

It is important to realize that leishmaniasis guidelines cannot always account for individual
variation among patients. They are not intended to supplant physician judgment with respect …

Cutaneous leishmaniasis is endemic in the tropics and neotropics. It is often referred to as a
group of diseases because of the varied spectrum of clinical manifestations, which range …

Governed by parasite and host factors and immunoinflammatory responses, the clinical
spectrum of leishmaniasis encompasses subclinical (inapparent), localised (skin lesions) …

Tegumentary leishmaniasis, comprising the cutaneous and mucocutaneous forms, is
caused by at least 13 dermotropic species of protozoa of the genus Leishmania, most of …

Pentavalent antimonials are first-line drugs for the treatment of the cutaneous form of
American tegumentary leishmaniasis. Second-line drugs include amphotericin B and …

The current interest in leishmaniasis stems from the importance of this disease with respect
to travel medicine, veterans of Operation Desert Storm, humanitarian concerns, and infection …

The diagnosis of leishmaniasis can be challenging because it mimics both infectious and
malignant conditions. A misdiagnosis may lead to an unfavorable outcome. Using culture …

The oral agent miltefosine has demonstrated a> 95% cure rate in Indian visceral
leishmaniasis. We performed a large, placebo-controlled study of miltefosine therapy (2.5 …