Many types of research have distinctly addressed the efficacy of natural plant metabolites used for human consumption both in cell culture and preclinical animal model systems …
Exemestane (EXE) is a novel oral steroidal aromatase inhibitor approved for the treatment of breast cancer. However, its oral clinical application is limited because of low aqueous …
S Gordon, M Daneshian, J Bouwstra, F Caloni… - …, 2015 - researchonline.ljmu.ac.uk
Models of the outer epithelia of the human body-namely the skin, the intestine and the lung- have found valid applications in both research and industrial settings as attractive …
Purpose The present study aimed to develop gefitinib-loaded solid lipid nanoparticles (GEF- SLN), and GEF-loaded PEGylated SLN (GEF-P-SLN) for targeting metastatic lung cancer …
İ Eroğlu, M İbrahim - Journal of drug targeting, 2020 - Taylor & Francis
Early researchers focussed on developing stimuli-responsive liposomes in order to manipulate drug release at the site of action or under certain conditions. In recent times, a …
S Banerjee, J Pillai - Expert opinion on drug metabolism & …, 2019 - Taylor & Francis
Introduction: Solid matrix mediated lipid nanoparticle formulations (LNFs) retain some of the best features of ideal drug carriers necessary for improving the oral absorption and …
In the present study, gold nanoparticles functionalized with anti HER-2 aptamer were designed for effective targeted delivery of dasatinib (DSB) to breast cancer cells. Anti HER-2 …
A Singh, YR Neupane, S Shafi, B Mangla… - Journal of molecular …, 2020 - Elsevier
In the rapidly expanding field of nanomedicine, liposomes have been considered as the most successful drug carrier having various clinically approved products. However, their …
The aim of this study was to design and fabricate nanostructured lipid carrier (NLC) for the potential oral delivery of decitabine (DCB). NLC was prepared by cold homogenization …