Head development in vertebrates involves a complex series of molecular and
morphogenetic events that generate a coordinated pattern of cartilages, bones and nerves …

The formation of the face and skull involves a complex series of developmental events
mediated by cells derived from the neural crest, endoderm, mesoderm, and ectoderm …

In a large-scale screen, we isolated mutants displaying a specific visible phenotype in
embryos or early larvae of the zebrafish, Danio rerio. Males were mutagenized with …

Zebrafish embryos and larvae have stage-specific patterns of motility or locomotion. Two
embryonic structures accomplish this behavior: the central nervous system (CNS) and …

Neural crest development involves cell-fate specification, proliferation, patterned cell
migration, survival and differentiation. Zebrafish neural crest derivatives include three …

To rapidly identify genes required for early vertebrate development, we are carrying out a
large-scale, insertional mutagenesis screen in zebrafish, using mouse retroviral vectors as …

Because of the genetic and developmental information available, Danio rerio stands out as
a vertebrate model system in which significant progress in the areas of development and …

We examined optokinetic and optomotor responses of 450 zebrafish mutants, which were
isolated previously based on defects in organ formation, tissue patterning, pigmentation …

Deletions of chromosome 1p36 affect approximately 1 in 5,000 newborns and are the most
common terminal deletions in humans. Medical problems commonly caused by terminal …

The neural crest (NC) is a major contributor to the vertebrate craniofacial skeleton, detailed
in model organisms through embryological and genetic approaches, most notably in chick …